God & Nature Magazine
  • 2025-#1 Issue
    • Letter from Editors 2025-1
    • Schrotenboer, Lying Dormant
    • Strauss, God Laughs & Smiles
    • Carr, Creation Stories
    • King, Falleness Physical World
    • Colon, A Hike
    • Thuraisingham, Identity
    • Bostrom 251 Every 6 Steps
    • Clifford 251, Just Starting Out
    • Johnson 251
    • Eyte, Touch
    • Budek-Schmeisser, Quitting
  • 2024-#4 (Fall) Issue
    • Letter from the Editors F24
    • Madison, 5 Smooth Stones
    • Dickenson, Genesis & Evolution
    • Berg, Is Genesis History?
    • Pinkham, Cells and Organs
    • Mitchell, Questions for AI
    • Taskinen, Alexander Grothendieck
    • Bostrom, On Camera F24
    • Clifford, Across the Pond F24
    • Johnson, Food for the Soul F24
    • Strand, Morning Prayer
    • Budek-Schmeisser, Sonrise
  • 2024-#3 (Summer) Issue
    • Letter from Editors Summer 24
    • Horst, Death through Adam
    • Bradley, Game Theory & Theology
    • Defoe, Science and Faith
    • Pickett, Wonder & Miracle
    • Touryan Wonder of Math
    • Wright, In The Beginning, God
    • Clifford Sum24
    • Johnson,, Summer 24
    • Eyte, Kaleidoscope
    • Budek-Schmeisser Bohemian Gravity
  • Past Issues
    • Spring 2024 Issue >
      • Editor's Letter Spring 2024
      • Miller, Sense of Place
      • Quick, Georg Cantor
      • Niemeyer, Research to Thriller
      • Carpenter, Creationism Inter-Textual
      • Defoe, Wittenberg Circle
      • Madison, Buttercups
      • Bostrom, Birds' Eye View
      • Clifford, What's the Use
      • Budek-Schmeisser, The Choice
      • Anderson, Van Gogh's Sunflowers
      • Lange, Summer Meadow
    • Winter 2024 Issue >
      • Garte and Albert W24
      • Fagunwa, Origen: Black Scientist
      • Gonzalez, Being Human
      • Defoe, A Pastor/s Journey
      • Curry, Birds of New Zealand
      • Lin, Environmental Problems
      • Garte, Genetics of Race
      • Pohl, Third Culture in Church
      • Bostrom, Mentors
      • Clifford, Hidden Figures
      • Albert; Poem. A Goldfish Sings a Tentative Psalm
      • Ardern Contact Points
    • Fall 2023 Issue >
      • Letter from Editors Fall 23
      • Owen, Mystery of the Trinity
      • Albert, Denialsim: A Case Study
      • King, Elements in the Bible
      • Carpenter, When was Day One?
      • Spaulding, Guided Differentiation
      • Greuel, Vision for the ACB
      • Bostrom, Lady Bugs
      • Clifford, Small Things
      • Gentleman, 30/80 Anno Domini
    • Summer 2023 Issue >
      • Letter from Editors Summer 23
      • Touryan, Feathers
      • Stenerson, Horseshoe Crabs
      • Hull, Evolving Scotus
      • Silva, Younger Ages
      • Williams, Dense Obscurity
      • Bostrom, Water Cries
      • Clifford, To Church Repair
      • Craig, Heavenly Lights
      • Valerius, Nothing to Something
      • Pinkham, Wisedrop
    • Spring 2023 Issue >
      • Letter from Editors Spring 2023
      • Rummo Lewis and the Cross
      • Pagan Biodiversity
      • Funck Assembly Theory and Life
      • Williams Thus Far
      • Mitchell Making Mistakes
      • Phillippy Living in Paradox
      • Bostrom Rain Shadow
      • Clifford Sustainable Cooking
      • Budek-Schmeisser, Completion
    • Winter 2023 Issue >
      • Letter From the Editors
      • Braden, A Modern Bestiary
      • Garte, Assembly Theory
      • Defoe, The Heavens Declare
      • Greenberg, Bonding
      • Barrigar, God's Big Story
      • Phillippy, Overcoming Paradox
      • Bostrom, Near
      • Clifford, Hidden Figures
    • Fall 2022 Issue >
      • Letter Fall22
      • Curry, Attentiveness
      • Russo, Deconstruction
      • Touryan, Four Forces
      • Mittchell, Three Words
      • Philippy, Math Theology Fall 22
      • Bostrom, Goodbyes
      • Clifford FAll 22
      • Linsley, Mystic Exile
      • Hall, A Call to Arms
    • Summer 2022 Issue >
      • Letter Summer 2022
      • Engelking, Neurotheology
      • Kelley, Environmentalism
      • Garte, Sandpipers
      • Madison, Cultivating Contentment
      • Collins, Answers on Evolution
      • Touryan, Tentmakers
      • Oord, Ever-Creative God
      • Bostrom, Mentors
      • Clifford, Carbon and Sin
      • Campbell, Just, In Time
    • Spring 2022 Issue >
      • Letter from the Editors Spring 2022
      • Curry, Knowldege and Truth
      • Pinkham, On a Car Emblem
      • Murray, Candling the Egg
      • Carr, Music, Math, Religion
      • Smith, Wonder and Longing
      • Linsky, Cyber Service
      • Bostrom, Buteo
      • Obi, Coincidences
    • Winter 2022 Issue >
      • Garte &Albert Letter Winter 2022
      • Thuraisingham Pondering Invisible
      • Cornwell Mediations from Molecular Biologist
      • Fagunwa Blsck Scientist & Church Father
      • Garte A Dialogue
      • Gonzalez Being Human
      • Klein Naturalist in Two Worlds
      • Bostrom Creeds
      • Clifford Winter 2022
      • Ardern Contact Points
      • Cooper Imagine No Christmas
    • Fall 2021 Issue >
      • Garte &Albert Letter Fall2021
      • Johnson, God Winks
      • Cottraux, Ancient Aliens
      • Arveson, Anti-Vax Email
      • Gammon, Evolutionary Insights
      • Mitchell, No One Told Me
      • Rummo, Faith in the Invisible
      • Bostrom, Fall Furrows
      • Lemcio, A Franciscan Weekend
      • Funk, Plant Haiku
      • Robinson & Lim, Who is God?
    • Summer 2021 Issue >
      • Garte &Albert Letter Sum2021
      • Warren, Immunization and Salvation
      • Defoe, Bernard Ramm
      • Cornwell Canine to Divine
      • Mix, Running with Nature
      • Pinkham, Scuba Divers
      • Cao, Physics and Bible
      • Bostrom, Sugar Birds
      • Clifford Sum21
      • Oostema, Evolution of Faith
      • Hall, Generation upon Generation
    • Spring 2021 Issue >
      • Garte and Albert Letter Spring 2021
      • Loikanen, Divine Action
      • Madison, Humus and Humility
      • Lappin, Puddles and Persons
      • Cornwell, God's GPS
      • Touryan, Contolled Fusion
      • Russo, Vaccine and Salvation
      • Bostrom, Short-eared Owl
      • Redkoles, Expect Unexpected
      • Clifford, Boring
      • McFarland, Imposition of Carbon
      • Lemcio, Manis Mastodon
    • Winter 2021 Issue >
      • Winter 2021 Contents >
        • Garte and Albert Letter from the Editors
        • Burnett How iit All Started
        • Isaac Director's Corner
        • Ruppel Herrington, First Editor
        • Burnett Origin of Lire
        • Hearn Balance
        • Middleton Natural Theology
        • Story Antibodies and Randomness
        • Lamoureux I Sleep a Lot
        • Warren Overloaded Brains
        • Isaac Knowledge of Information
        • Bancewicz Wonder and Zebrafish
        • Oord Photoessay
        • Albert Hope in Winter
        • Clifford Storytelling & Drama in Teaching
        • Pohl The Column (Poetry)
    • Fall 2020 Issue >
      • Letter from Editors
      • Pohl, Panpsychism and Microbiome
      • Reyes, Communion During Loss
      • Griffin, Hands On
      • Azarvan, Science and Limits
      • Cornwell, Search Engines for God
      • Thuraisingham, Duality of Humans and Particles
      • Touryan, Prayers of Petition
      • George, Perfect Vision
      • Declare the Glory, Green: Awe
      • Bostrom Purpose
      • Oord, Theological Photoessay
      • Clifford, Food, Water, Waste
    • Summer 2020 Issue >
      • Summer 2020 Contents >
        • Editors Letter Summer2020
        • Jones, Science Faith Duopoly
        • Mix, God and the Virus
        • Warner, COVID-19 and Goodness of Creation
        • Gonzalez, Pandemic and Groaning of Creation
        • Johnson, Star Wars Food
        • Pyle, It Takes a (Medical ) Village
        • Arveson, Use for 3D Printers
        • Peterson, Pandemic and Research
        • Zeidan, Mentorship Online
        • Oleskeiwicz, Dragonfly on Water
        • Carr, COVID-19 and Climate Change
        • Nierrman, The Squirrel
        • Cornwell, COVIS-19 Bucket List
        • Bostrom, Grass Thoughts
        • Clifford, Summ20 Conflict
    • Spring 2020 Issue >
      • Letter from the Editors SP20
      • AD
      • Murphy, Nature and Calvary
      • Dickin, The Flood and Genesis 1
      • Gruenberg, Empiricism and Christian Spirituality
      • Ungureanu, Science, Religion, Protestant Tradition
      • Russo, How does it End?
      • Siegrist, Problems with Materialism
      • Ohlman, 20/20 in 2020
      • Warren, Rock Frogs
      • Edwards, Sanctuary
      • Bostrom, Clothed
      • Clifford, The Lent of Lockdown Spring 2020
      • Hall, 1:30 AM on a Tuesday (Poem)
    • Winter 2020 Issue >
      • Letter from the Editor Winter 2020
      • AD
      • Wimberly Inheritance, Meaning and Code
      • Defoe; A Pastor's Journey
      • Mix The Ends of the World
      • Pevarnik Limits of Physics
      • Greenberg "Godly" Science
      • Pinkham Teleological Thinking
      • Alexanian How to Witness
      • "Declare the Glory" Neal, Cross, Gait
      • Clifford "Across the Pond" Winter 2020
      • Oord "Theological Photoessays" Winter 2020
      • Salviander The Objective Man (Poem)
      • Ohlman Orphan of the Universe (Poem)
      • Lemcio Grey's Anatomy (Poem)
    • Fall 2019 Issue >
      • Letter from the Editor Fall 2019
      • Phillippy Mathematics and God
      • Pohl & Thoelen Databases
      • Garte Limits of Science
      • Mitroka Healthy Lifestyle
      • Sigmon Science and Revelation
      • Mariani Compatibility Creation and Evolution
      • Anders Theistic Evolution
      • Touryan Are we alone
      • Johnson Purpose and Source
      • Declare the Glory Curry, Smith, Best
      • Clifford "Across the Pond" Fall 19
      • Oord "Theological Photoessays Fall 19
      • Eyte Cross Cascade "Poem"
    • Summer 2019 Issue >
      • Letter from the Editor Summer 2019
      • Arveson Is There a “Theory of Everything”
      • Anderson The History and Philosophy of Science and Faith
      • Tolsma Science in Church
      • Salviander Black Holes and Atheism
      • Johnson Practical Problems for Literal Adam
      • Hall God and the Assumptions of Scientific Research
      • Linsky Overcoming Misconceptions
      • Wilder Sanctity of Creation
      • Clifford "Across the Pond" Summer19
      • Oord "Theological Photoessays" Summer 2019
      • Flaig Time and Me (Poem)
    • Spring 2019: Creation Care and Environment >
      • Letter from the Editor Spring 2019
      • Bancewicz;Sustainability Pledge: Why the Environment is My Problem
      • Lin; Environmental Problems as a Place for Compromise and Dialogue
      • Garvey; Where the Fall Really Lies
      • Lewis; Solar-Powered Life: Providing Food, Oxygen and Protection
      • Garte; Time and Human Impact on the Environment
      • Mays; Reforming Science Textbooks
      • Carr; Cosmic Energy First, Then Matter: A Spiritual Ethic
      • Kincanon; The Young Earthers and Leibniz
      • Declare the Glory Gauger
      • Clifford "Across the Pond" Spring 2019
      • Oord; Photoessay. Theological Photo Essays
      • Rivera; Photoessay. Digital Artwork: Images of Jesus
      • Albert; Poem. A Goldfish Sings a Tentative Psalm
      • Armstrong; Poem Holy Sonnet XI
    • Winter 2019: Education and Outreach 2 >
      • Letter from the Editor, Winter 2009
      • Applegate; Project Under Construction: Faith Integration Resource for High School Biology
      • LaBelle; Sidewalk Astronomy Evangelism - Taking it to the Streets!
      • Reed; Speaking to the Heart and Mind of Students about Evolution and Creation
      • Marcus; The Conflict Model
      • Rivera; The Implicit Assumptions behind Hitchen's Razor
      • Russo; Redeeming Bias in Discussion of Science and Faith
      • Fischer; Origins, Genesis and Adam
      • Clifford Column, Winter 2019
      • Gait; Photoessay - Stripes
      • Lee; Poem. In Chaos and Nothingness
    • Fall 2018: Education and Outreach 1 >
      • Letter from the Editor Fall 2018
      • Glaze; A Walk within Two Worlds: Faith, Science, and Evolution Advocacy
      • Johnson; Teaching the Controversy in Texas
      • Cootsona; Mere Christianity, Mainstream Science and Emerging Adults
      • Kindstedt; Creating a Third Culture
      • Zeidan; An Effective Way to Integrate Supportive Communication and Christian Belief into Virtual Classrooms
      • Marshall; A New Model of Causation
      • McClure; Nothing in the Bible Makes Sense Except in the Light of Grace
      • Frank; Christianity, Science and Teamwork
      • Assad/Reyes; Interview. Discovering a Renewed Sense of Awe and Wonder about God
      • Clifford Column Fall 2018
      • Menninga; Photoessay. What do These Stones Mean?
    • Summer 2018: Judgment and Peer Review >
      • Letter from the Editors Summer 2018
      • Jones; Peer Review: Avoiding Judgmentalism
      • Arnold; Discovering Spiritual Information Through Peer-Reviewed Science
      • Peterson; Peering at Double-Blind Peer Review
      • Smith; A Philosophical Influence from the Scientific Revolution on Scientific Judgment
      • Mix; The Poetry of Probability
      • Mobley; Randomness vs. the Providence of God?
      • Gordon; Chances are Good: Design and Chance in Genesis 1
      • Siegrist; But the Multiverse...!
      • Reyes; The Community Table: Interview with Marianne Johnson
      • Clifford Column Summer 2018
      • Hill; Poem. Synthesis
      • Lemcio; Poem. I Could See Where This was Going
      • Oord: Photoessay
    • Spring 2018: Chance & Design >
      • Letter from the Editors
      • Bishop; God, Love and Chance
      • Bonham; Quantum Reflections
      • Spaulding; God as Designer
      • Garte; Teleology in Evolution
      • Hall; God, Chance and Buridan's Ox
      • Pohl; Why We Need a Third Culture in Church
      • Dorman; Liturgical Brain
      • Warren; Galapagos
      • Blanchard; On Christian Science
      • Touryan; The Cross as a Cosmic Filter
    • Winter 2018: Race & Inheritance >
      • A Note from the Editors
      • Essay: “Some Pastoral Considerations of CRISPR CAS 9 Gene Editing” by Mario A Russo
      • Essay: “The Genetics and Theology of Race” by Sy Garte
      • Essay: "Grieve the Segregation of Science" by S. Joshua Swamidass
      • Poem: "Cardboard Man" by Ciara Reyes
      • Featured Interview: “Love Is Risk” with Carolyn Finney
      • Essay & Poem: “Abortion Languages: Love, fear, confusion and loss”
      • Essay: "Why the Church Needs Intersectional Feminism" by Emily Herrington
      • Essay: “Elected to Salvation (and other things?)” by Bill Leonard
      • Essay: “Local Colour: A reflection on family, history, and heritage” by Mike Clifford
      • Interview: Corina Newsome, environmentalist and animal keeper
      • Essay: “Spiritual Kin Selection” by Steve Roels
      • Photo Essay: "Trouble in Paradise: Plastic pollution in the Bahamas" by Grace Swing & Robert D Sluka
      • Essay: “Race & Inheritance: Personal reflections and annotations” by Walt Hearn
      • Interview: Carla Ramos, molecular biologist
      • Clifford Column; Discipine Hopping
      • Lemcio; Waves
      • Harris Artwork
      • Hearn; Eulogy - Beyond Science,
    • Summer 17: Cosmology & Theology >
      • Letter from the Editors: Summer 2017
      • Essay: "The News from My Home Galaxy" by Walt Hearn
      • Interview: "Deep Incarnation & the Cosmos: A Conversation with Niels Henrik Gregersen" by Ciara Reyes & Niels Henrik Gregersen
      • Photo Essay: "Breath & Dust" by Kathleen Eady
      • Essay: "Why the Eagle Nebula Just Doesn’t Do It For Me" by Mike Clifford
      • Essay: "The Cosmos in My Hand" by Lucas Mix
      • Interview: “What is Life? On Earth and Beyond” with Andreas Losch
      • Artwork by Missy Pellone
      • Essay: "When God & Science Hide Reality" by Davis Woodworth
      • Essay: "​In Search of Wonder: A Reflection on Reconciling Medieval and Modern Cosmology" by Monica Bennett
      • Essay: "If Christianity and Cosmology Are in Conflict, Whose Side Is Philosophy on?" by Vaughan Rees
    • Winter/Spring 17: "Flesh & Blood" >
      • Letter from the Editor: Winter/Spring 2017
      • Essay: "Probiotics, Prebiotics, Synbiotics: On microbiomes and the meaning of life" by John F. Pohl
      • Essay: "With All Your Mind" by Paul S. Kindsedt
      • Essay: "The Stuff of Life" by Mike Clifford
      • Essay: "Experiencing God’s Love in a Secular Society: A Christian experience with socialized medicine" by Alison Noble
      • Poem: "The Problem with Pain" by Eugne E. Lemcio
      • Essay: "Thoughts of Death in a Cruel World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht and Emily Herrington
      • Essay: "Tissues at Issue" by Walt Hearn
      • Essay: "The Dilemma of Modern Christianity" by Tony Mitchell
      • Poem: "Light" by Billie Holladay Skelley
      • Essay: "Some Theological Implications of Science: Revisiting the Ant" by Mario A. Russo
    • Summer/Fall 16: "Stewardship of Words" >
      • Letter from the Editor: Summer 2016
      • Levity: "Walt Being Walt: Excerpts from the ASA newsletter" by Walt Hearn (compiled by Jack Haas & Emily Ruppel)
      • Poem: "A Prayer Tribute to Walt and Ginny Hearn" by Paul Fayter
      • Essay: "Authentic Science & Authentic Christian Faith" by Paul Arveson
      • Essay: "On Modern-Day Saints & Epistles" by Emily Ruppel
      • Essay: "​Mathematics and the Religious Impulse" by Karl Giberson
      • Poem: "The Wasteful Gene" by Eugne E. Lemcio
      • Three Poems by Dan Eumurian
      • Excerpts from: "The Dictionary of Daily Life in Biblical and Post-Biblical Antiquity" by Edwin Yamauchi
      • Essay: "A Comprehensible Universe: The blessing from God that makes science possible" by Bob Kaita
      • Poem: "The Epistolarian" by Emily Ruppel
    • Spring 16: "Brain Science" >
      • Letter from the Editor: Spring 2016
      • Essay: "Ancient Q, Modern A (?)" by Walt Hearn
      • Essay: "Souls, Brains and People: Who or what are we?" by Gareth D. Jones
      • Essay: "A Functional Theology of Psychopathology" by Edgar Paul Herrington IV
      • Three Poems by Richard Gillum
      • Essay: "Thoughts of Death in an Unkind World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht
      • Short Story: "Malefic" by Jeffrey Allen Mays
      • Essay: "An Engineer Visits a Mindfulness Workshop" by Mike Clifford
      • Essay: "Traces of Trauma in the Body of Christ: The case of The Place of Refuge" by Elizabeth Hernandez
      • Essay: "Did God ‘Create’ Science? Christianity and the uniqueness of the human brain" by William H. Church
    • Winter 16: "Quantum Physics/Epigenetics" >
      • Letter from the Editor: Winter 2016
      • Essay: "God and the New Evolutionary Biology" by Sy Garte
      • Essay: "Quantum Mechanics and the Question of Divine Knowledge" by Stephen J. Robinson
      • Essay: "Creation Out of... Physics?" by Joshua Scott
      • Essay: "Of Books and Bosons" by Mike Clifford
      • Essay: "Words, Words, Words" by Walt Hearn
      • Poem: "Encountering Ernst Haeckel’s 'Ontogeny Recapitulates Phylogeny'" by Eugene Lemcio
      • Essay: "The Extended Evolutionary Synthesis: New conversations and theological questions at the horizons of modern science" by Michael Burdett
      • Poem: "The Difference" by Emily Ruppel
      • Essay: "Maupertuis's Ghost: Finding God in 'action'" by Colin C. Campbell
    • Fall 15: "Technology" >
      • Letter from the Editor: Fall 2015
      • Essay: "‘Braving the New World (Wide Web): Mapping Theological Response to Media" by Justin A. Bailey
      • Poem: "Entropy and Enthalpy" by Glenn R. McGlaughlin
      • Essay: "‘How Proactive Should Christians Be in Learning about Emerging Biomedical Technologies?" by D. Gareth Jones
      • Essay: "‘Can We Fix It? Erm..." by Mike Clifford
      • Poem: "To My Dear Parents" by Sarah Ruden
      • Essay: "‘Which Side, Lord?" by Walt Hearn
      • Poem: "The Column" by John F. Pohl
      • Essay: "‘Technology and the Church" by Derek Schuurman
      • Poem: "On the Shores of Oroumieh" by Emily Ruppel
      • Essay: "‘Technology as Discipline" by Johnny Wei-Bing Lin
    • Summer 15: "Doubt" >
      • Letter from the Editor: Summer 2015
      • Essay: "‘The Road Not Taken’: A personal reflection on careers, counterfactuals and callings" by Tim Middleton
      • Essay: "The Gift of Doubt in My Life" by Rev. Paul Herrington
      • Poem: "The Marsh Birds" by Sarah Ruden
      • Essay: "On St Brendan and the Pendulum of Postgraduate Study" by Mike Clifford
      • Essay: "Doubt: The Invisible Conversation" by Karl W. Giberson
      • Essay: "Doubt, Faith, and Crevasses on My Mind" by Peter M. J. Hess
      • Poem: "Magdalene" by Leonore Wilson
      • Essay: "Breaking Barriers, Ministering in Relationships, and Exemplifying the Gospel" by Stephen Contakes, et al.
      • Poem: "On the Extinction of Matter Near a Black Hole" by Ruth Hoppin
      • Essay: "Sometimes I Doubt..." by Walt Hearn
      • Essay: "The Risks of Love and Life's Big Questions" by Thomas Jay Oord
    • Spring 15: "Animals/Imago Dei" >
      • Letter from the Editor: Spring 2015
      • Essay: "50 Years of Wilderness: a Christian perspective" by Peter van der Burgt
      • Essay: "All Creatures Great and Small " by Walt Hearn
      • Essay: "Let There Be Less: A Christian musing on nature, faith, and farmers’ markets" by Emily Ruppel
      • Poem: "The New Plant and Animal Kingdoms" by Steve Roels
      • Essay: "Of Wonder and Zebrafish" by Ruth Bancewicz
      • Essay: "The Lion, the Spider and the Image of God" by Mike Clifford
      • Cat Poem 1: "Lullaby for Stomp the Cat" by Sarah Ruden
      • Cat Poem 2: "Letting the Dog In" by Emily Ruppel
      • Cat Poem 3: "Reading on the Couch" by Carol Ruppel
      • Essay: "Angry Discussions: A Wrong Way to Stand for Creation Care or Science Advocacy " by Oscar Gonzalez
      • Essay: "Ethical Eating on a Catholic Campus: Some thoughts from a student of environmental studies" by Grace Mican
    • Winter 15: "Information" >
      • Letter from the Editor: Winter 2015
      • Essay: "What Does it Mean to Know?" by Mark Shelhamer
      • Essay: "Knowledge of Information" by Randy Isaac
      • Photo Essay: "Being Here" by Carol Ruppel
      • Essay: "Truth Anyone?" by Walt Hearn
      • Poem: "Transformation" by Ruth Hoppin
      • Interview: "Unpacking Chance, Providence, and the Abraham's Dice Conference" by Olivia Peterson
      • Essay: "On Knowledge and Information–Tales from an English childhood" by Mike Clifford
      • Poem: "Space Travel" by Ruth Hoppin
      • Essay: "Resuming the Science/Faith Conversation" by Jamin Hubner
    • Archives >
      • Past Contributors
      • Fall 14: "History of Science & Christianity" >
        • Letter from the Editor: Fall 2014
        • Essay: "Orchids: Why the founders of modern science cultivated virtue" by Ruth Bancewicz
        • Essay: "Science Falsely So Called: Fundamentalism and Science" by Edward B. Davis
        • Essay: "The Other 'Atom' in Christianity and Science" by Karissa D Carlson
        • Poem: "The Hermit" by Ciara C. Reyes
        • Essay: "Players" by Walt Hearn
        • Essay: "Using Storytelling and Drama in Engineering Lectures" by Mike Clifford
        • Essay: "Is There Anything Historical About Adam and Eve?" by Mike Beidler
        • Essay: "Finding Harmony in Controversy: The early years of the ASA" by Terry Gray and Emily Ruppel
        • Levity: "Fish n' Chips" by Mike Arnold
        • Essay: "Stories" by Walt Hearn
      • Summer 14: "Christian Women in Science" >
        • Letter from the Editor: Summer 2014
        • Essay: "I Really Did That Work: A brief survey of notable Christian Women in Science" by Lynn Billman
        • Essay: "He + She = We" by Walt Hearn
        • Photo Essay: "The Faces of Nature" by Susan Limone
        • Essay: "On Grass that Withers: Overloaded brains and spiritual discernment" by Janet Warren
        • Interview: "Ancient Humans and Modern Choices" with Briana Pobiner
        • Essay: "Crystallographer, Quaker, Pacifist, & Trailblazing Woman of Science: Kathleen Lonsdale’s Christian Life 'Lived Experimentally'” by Kylie Miller and Stephen M. Contakes
        • Artwork: "Eden, Zion" by Harold Sikkema
        • Essay: "Asking the Right Question" by Dorothy Boorse
        • Interview: "Not So Dry Bones" with Mary Schweitzer
        • Essay: "Is Being a Mother and a Scientist Worth It?" by Abby Hodges
        • Essay: "Playing God: A theological reflection on medicine, divine action, and personhood" by Ann Pederson
        • Column: Great Gravity! "BNL 1976 – 2000 (Part 1)"
      • Spring 14: "G&N: The 2-year tour" >
        • Letter from the Editor: Spring 2014
        • Essay: "Political Science?" by Walt Hearn
        • Comic: "Education"
        • Essay: "Finding Hominids with Kamoya Kimeu" by Fred Heeren
        • Poem: "Ziggurat (and Helix)" by Amy Chai
        • Creative Nonfiction: "One Summer" by Dave Harrity
        • Essay: "Do the Heavens Declare the Glory of God?" by Owen Gingerich
        • Comic: "Miracle Mechanics" by Emily Ruppel
        • Essay: "I Sleep A Lot" by Denis O. Lamoureux
        • Poem: "Angels and RNA" by Walt Hearn
        • Comic: "Seminary"
        • Essay: "The Elegance of Antibodies" by Craig M. Story
        • Photo Essay: "Conversing with Nature" by Thomas Jay Oord
        • Essay: "Under the Tutelage of Trees: Arboreal Lessons on Virtue, Kinship, and Integrity" by Peter M. J. Hess
        • Comic: "Humor"
        • Essay: "Science and Scientism in Biology" by Sy Garte
        • Interview: "Biopsychology and Faith" with Heather Looy
      • Winter 14: "Health & Medicine" >
        • Letter from the Editor: Winter 2014
        • Poem: I Have a Piece of Cow in My Heart
        • Essay: Acts of God: Are all mutations random?
        • Column: Beyond Science
        • Poem: Psalm 1859
        • Essay: The Tao of Departing
        • Essay: The Tao of Departing p 2
        • Photo Essay: Walking in Winter
        • Essay: A Christian Doctor on Evolution, Faith, and Suffering
        • Opinion: Making Friends with Frankencorn
        • Poem: Chiaroscuro
        • Interview: "Biopsychology and Faith" with Heather Looy
        • Essay: "The Elegance of Antibodies"
        • Artwork: "Helix" by Harold Sikkema
        • Column: Great Gravity! "Dissertations and Revelations"
      • Fall 13: "Environmentalism" >
        • Letter from the Editor: Fall 2013
        • Poem: Time
        • Essay: Is there Hope for the Ocean?
        • Artwork: "Earthly Tent" by Harold Sikkema
        • Essay: What is Responsible Eating?
        • Essay: Are We Too Obsessed with Food?
        • Poem: Conversation on Creation
        • Essay: Creation Care from the Perspective of a Conservation Geneticist
        • Essay: Mobilizing Scientists for Environmental Missions
        • Poem: Paleocene Spring
        • Interview: Dorothy Boorse
        • Column: Beyond Science
        • Essay: New Testament Motivation for Environmental Stewardship
        • Poem: Stone of House
        • Column: Great Gravity! "Running the Data"
      • Summer 13: "Science & Creativity" >
        • Column: Beyond Science
        • Letter from the Editor: Summer 2013
        • Column: Faith on the Field
        • Poem: Trying Not to Be Too Sunny
        • Comic: "Work in Progress"
        • Essay: Do the Heavens Declare the Glory of God?
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God and Nature ​                                                                                Winter 2023


​Assembly Theory and Abiogenesis

​

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By Sy Garte

Astrobiology is an interesting field of science. It is based more on hope and belief than on hard evidence that life exists elsewhere in the universe, and that we might be able to find and study it. There is reason for this belief—mainly, the huge number of planets in our own galaxy, and the statistical likelihood that many (maybe millions) of these planets have the necessary conditions for life (the right size, right position, right composition, etc.).

One of the major goals of astrobiology is to come up with techniques that could allow scientists on earth to be able to detect the presence of life remotely, without needing to actually go to extremely distant planets. A recent paper in Nature (1) reports on a novel and very promising approach to life detection that has the advantage of making no assumptions about the nature of alien life other than it is composed of chemicals. That is, at least to me, a perfectly valid assumption, since most of the alternatives proposed in various science fiction scenarios have too many irreconcilable difficulties to be believed.

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The approach is called Assembly Theory, and it is based on a fairly simple premise, although the details are far from simple. I will not go into those here—they can be found in the Nature paper. My purpose instead is to present the basic idea of the theory in summary, go over some of the results, and discuss the implications for another, equally difficult area of biological science—the origin of life.
​

Assembly theory hypothesizes that living creatures are capable of synthesizing more complex (and larger) molecules than can be made spontaneously by abiotic (nonliving) chemical and physical processes. The paper (1) presents both a theoretical approach to calculation of a complexity factor called the molecular assembly index (MA), and an experimental method to determine the MA value of any chemical using a form of mass spectroscopy (MS). There is good agreement between the calculated and experimental results. The authors also tested the ability of the MA value of complexity to distinguish chemicals that we know originated from life from those that did not.


FIGURE 1 The abiotic (nonliving) molecules are in pink and the biotic (from life) molecules are in green.

The results are very impressive, and show that a complexity level of MA = 15 is the maximum that can be achieved by abiotic chemical synthesis. In contrast, molecules from life span the entire range of MA values, including far above the MA = 15 limit for nonliving sources,l as shown above in Figure 1 (Figure 4A in the 
Nature paper). The experiment tested over a million chemicals from many sources. In no case did any non-biological chemical surpass the MA = 15 barrier. This means that an analysis of a planet’s chemical composition could determine the presence of life if any signal greater than MA = 15 were detected using a MS machine.

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The details of calculation of the MA index are complicated. In short, the basic algorithm involves counting bonds between atoms and adding them. But repetitive chemical elements are accounted for separately, so the total value of the MA is dependent on how many and what size various repetitive elements exist in a molecule. Details and examples can be found in the Supplementary Material (2).

So what kind of chemicals can be formed outside of life, and what are the kinds that cannot? All of the amino acids have MA scores less than 15, consistent with experimental demonstrations that amino acids can be formed outside of life. The same may be said for most dipeptides, compounds composed of two amino acids linked together. But when we look at tripeptides, things get messier. A set of three different amino acids linked together is more likely to have an MA score above 15 than below it. And with larger peptides (four or more amino acids), the score is almost always above 15. This point is not thoroughly explored in the paper, but it is consistent with the data in Figure 2 (Figure 4C in the Nature paper) showing the results for two dipeptides and for a mixture of “urinary peptides” that are not further characterized but presumably represent a wide range of peptide sizes and compositions. 

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FIGURE 2 The first two columns show dipeptides, and third is a mix of peptides from urine.


​That’s a problem for the assumption of a purely chemical abiogenesis. The most commonly held current view in origin-of-life research is that an RNA-peptide world (rather than just RNA world) came before modern DNA-based life. But such a scenario envisages abiotic synthesis of peptides composed of at least 5-8 amino acids. The assumption that peptides with that degree of complexity could be easily produced from amino acids is questioned by these results on a complexity limit on abiotic molecules.

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But things are much worse for the RNA side of the hypothesis. It turns out that the MA score for adenosine triphosphate (ATP, one of the four building blocks of polynucleotides, the precursors of RNA long polymers) is 21 (see Figure 3 from the linked video (3)), far above the abiotic limit. And, of course, this implies that even dinucleotides, let alone small stretches of RNA, could not occur outside of life, at least not in significant quantities.



FIGURE 3 The structure of ATP, a basic building block of RNA and DNA, with MA = 21
​
I want to thank YouTuber John Maddox for alerting me to this paper and sparking my interest in what these results could mean for abiogenesis based on purely chemical processes. While the authors’ focus in this work is the detection of life on exoplanets, not the origin of life, I believe the implications of a cutoff of complexity beyond a particular threshold for abiotic chemical synthesis are profound, perhaps even revolutionary.


I should add that the senior author of this paper is certainly not someone who doubts the reality of naturalistic abiogenesis based solely on random interactions of chemicals, nor is he  a skeptic about early precursors to polymer construction before life began. It is British chemist Lee Cronin, a man who has engaged in lively (to use a polite term) debate with abiogenesis skeptic James Tour, a synthetic organic chemist and a Christian.

I saw no comment from Cronin or any of the other authors of the paper, either in follow up papers or in a video describing the work (3), mentioning what to me look like dramatic implications of this research for the origin-of-life paradigms currently being explored in many labs.

One possible reason for this silence may be that I am misinterpreting the findings of the paper, and there are in fact no such negative implications. Perhaps the results have no bearing on the likelihood of a purely chemical origin of life. For example, it could be that the upper limit of 15 for chemical complexity from abiotic synthesis is not completely rigid, and that rare examples of decapeptides and 20-50-member polynucleotide chains (without branching due to 5’ to 2’ bonding) can be constructed outside of life. The authors in fact emphasize that their interest is not in the absolute probability of a specific molecule ever forming—rather, it is the complex molecules’ presence in abundant quantities that an astrobiologist would look for as a marker for life. Perhaps a few extremely rare abiotically formed molecules can find a way to avoid hydrolysis, become stable by interacting with each other, and then… I don’t know, maybe some process could lead to further synthesis and concentration of such molecules.
​
I would welcome any comments or suggestions from readers on this subject, as I am only a biochemist who is very likely missing something here. I promise that all such commentary will be promptly published in the magazine (I have a special relationship with the Editor-in-Chief) for the further enlightenment of our readers.  

References

1. Marshall, S.M., Mathis, C., Carrick, E. et al. Identifying molecules as biosignatures with assembly theory and mass spectrometry. Nat Commun 12, 3033 (2021).

2. 
https://static-content.springer.com/esm/art%3A10.1038%2Fs41467-021-23258-x/MediaObjects/41467_2021_23258_MOESM1_ESM.pdf

3. Universal Life Detection: Astrobiology & Assembly Theory
NASA Astrobiology 9/2/2021 Link



Sy Garte, Ph.D. Biochemistry, is Editor-in-Chief of God and Nature, and the author of The Works of His Hands: A Scientist's Journey from Atheism to Faith. He is currently Visiting Professor at Rutgers University and has been a Professor of Public Health and Environmental Health Sciences at three universities. He was an Associate Director at the Center for Scientific Review at the NIH. He blogs at The Book of Works, and his website is sygarte.com.  Sy is Vice President of the Washington DC ASA Chapter, and a fellow of the ASA. ​

God & Nature magazine is a publication of the American Scientific Affiliation, an international network of Christians in science: www.asa3.org