God & Nature Magazine
  • Spring 2023 Issue
    • Letter from Editors Spring 2023
    • Rummo Lewis and the Cross
    • Pagan Biodiversity
    • Funck Assembly Theory and Life
    • Williams Thus Far
    • Mitchell Making Mistakes
    • Phillippy Living in Paradox
    • Bostrom Rain Shadow
    • Clifford Sustainable Cooking
    • Budek-Schmeisser, Completion
  • Winter 2023 Issue
    • Letter From the Editors
    • Braden, A Modern Bestiary
    • Garte, Assembly Theory
    • Defoe, The Heavens Declare
    • Greenberg, Bonding
    • Barrigar, God's Big Story
    • Phillippy, Overcoming Paradox
    • Bostrom, Near
    • Clifford, Hidden Figures
  • Fall 2022 Issue
    • Letter Fall22
    • Curry, Attentiveness
    • Russo, Deconstruction
    • Touryan, Four Forces
    • Mittchell, Three Words
    • Philippy, Math Theology Fall 22
    • Bostrom, Goodbyes
    • Clifford FAll 22
    • Linsley, Mystic Exile
    • Hall, A Call to Arms
  • Past Issues
    • Summer 2022 Issue >
      • Letter Summer 2022
      • Engelking, Neurotheology
      • Kelley, Environmentalism
      • Garte, Sandpipers
      • Madison, Cultivating Contentment
      • Collins, Answers on Evolution
      • Touryan, Tentmakers
      • Oord, Ever-Creative God
      • Bostrom, Mentors
      • Clifford, Carbon and Sin
      • Campbell, Just, In Time
    • Spring 2022 Issue >
      • Letter from the Editors Spring 2022
      • Curry, Knowldege and Truth
      • Pinkham, On a Car Emblem
      • Murray, Candling the Egg
      • Carr, Music, Math, Religion
      • Smith, Wonder and Longing
      • Linsky, Cyber Service
      • Bostrom, Buteo
      • Obi, Coincidences
    • Winter 2022 Issue >
      • Garte &Albert Letter Winter 2022
      • Thuraisingham Pondering Invisible
      • Cornwell Mediations from Molecular Biologist
      • Fagunwa Blsck Scientist & Church Father
      • Garte A Dialogue
      • Gonzalez Being Human
      • Klein Naturalist in Two Worlds
      • Bostrom Creeds
      • Clifford Winter 2022
      • Ardern Contact Points
      • Cooper Imagine No Christmas
    • Fall 2021 Issue >
      • Garte &Albert Letter Fall2021
      • Johnson, God Winks
      • Cottraux, Ancient Aliens
      • Arveson, Anti-Vax Email
      • Gammon, Evolutionary Insights
      • Mitchell, No One Told Me
      • Rummo, Faith in the Invisible
      • Bostrom, Fall Furrows
      • Lemcio, A Franciscan Weekend
      • Funk, Plant Haiku
      • Robinson & Lim, Who is God?
    • Summer 2021 Issue >
      • Garte &Albert Letter Sum2021
      • Warren, Immunization and Salvation
      • Defoe, Bernard Ramm
      • Cornwell Canine to Divine
      • Mix, Running with Nature
      • Pinkham, Scuba Divers
      • Cao, Physics and Bible
      • Bostrom, Sugar Birds
      • Clifford Sum21
      • Oostema, Evolution of Faith
      • Hall, Generation upon Generation
    • Spring 2021 Issue >
      • Garte and Albert Letter Spring 2021
      • Loikanen, Divine Action
      • Madison, Humus and Humility
      • Lappin, Puddles and Persons
      • Cornwell, God's GPS
      • Touryan, Contolled Fusion
      • Russo, Vaccine and Salvation
      • Bostrom, Short-eared Owl
      • Redkoles, Expect Unexpected
      • Clifford, Boring
      • McFarland, Imposition of Carbon
      • Lemcio, Manis Mastodon
    • Winter 2021 Issue >
      • Winter 2021 Contents >
        • Garte and Albert Letter from the Editors
        • Burnett How iit All Started
        • Isaac Director's Corner
        • Ruppel Herrington, First Editor
        • Burnett Origin of Lire
        • Hearn Balance
        • Middleton Natural Theology
        • Story Antibodies and Randomness
        • Lamoureux I Sleep a Lot
        • Warren Overloaded Brains
        • Isaac Knowledge of Information
        • Bancewicz Wonder and Zebrafish
        • Oord Photoessay
        • Albert Hope in Winter
        • Clifford Storytelling & Drama in Teaching
        • Pohl The Column (Poetry)
    • Fall 2020 Issue >
      • Letter from Editors
      • Pohl, Panpsychism and Microbiome
      • Reyes, Communion During Loss
      • Griffin, Hands On
      • Azarvan, Science and Limits
      • Cornwell, Search Engines for God
      • Thuraisingham, Duality of Humans and Particles
      • Touryan, Prayers of Petition
      • George, Perfect Vision
      • Declare the Glory, Green: Awe
      • Bostrom Purpose
      • Oord, Theological Photoessay
      • Clifford, Food, Water, Waste
    • Summer 2020 Issue >
      • Summer 2020 Contents >
        • Editors Letter Summer2020
        • Jones, Science Faith Duopoly
        • Mix, God and the Virus
        • Warner, COVID-19 and Goodness of Creation
        • Gonzalez, Pandemic and Groaning of Creation
        • Johnson, Star Wars Food
        • Pyle, It Takes a (Medical ) Village
        • Arveson, Use for 3D Printers
        • Peterson, Pandemic and Research
        • Zeidan, Mentorship Online
        • Oleskeiwicz, Dragonfly on Water
        • Carr, COVID-19 and Climate Change
        • Nierrman, The Squirrel
        • Cornwell, COVIS-19 Bucket List
        • Bostrom, Grass Thoughts
        • Clifford, Summ20 Conflict
    • Spring 2020 Issue >
      • Letter from the Editors SP20
      • AD
      • Murphy, Nature and Calvary
      • Dickin, The Flood and Genesis 1
      • Gruenberg, Empiricism and Christian Spirituality
      • Ungureanu, Science, Religion, Protestant Tradition
      • Russo, How does it End?
      • Siegrist, Problems with Materialism
      • Ohlman, 20/20 in 2020
      • Warren, Rock Frogs
      • Edwards, Sanctuary
      • Bostrom, Clothed
      • Clifford, The Lent of Lockdown Spring 2020
      • Hall, 1:30 AM on a Tuesday (Poem)
    • Winter 2020 Issue >
      • Letter from the Editor Winter 2020
      • AD
      • Wimberly Inheritance, Meaning and Code
      • Defoe; A Pastor's Journey
      • Mix The Ends of the World
      • Pevarnik Limits of Physics
      • Greenberg "Godly" Science
      • Pinkham Teleological Thinking
      • Alexanian How to Witness
      • "Declare the Glory" Neal, Cross, Gait
      • Clifford "Across the Pond" Winter 2020
      • Oord "Theological Photoessays" Winter 2020
      • Salviander The Objective Man (Poem)
      • Ohlman Orphan of the Universe (Poem)
      • Lemcio Grey's Anatomy (Poem)
    • Fall 2019 Issue >
      • Letter from the Editor Fall 2019
      • Phillippy Mathematics and God
      • Pohl & Thoelen Databases
      • Garte Limits of Science
      • Mitroka Healthy Lifestyle
      • Sigmon Science and Revelation
      • Mariani Compatibility Creation and Evolution
      • Anders Theistic Evolution
      • Touryan Are we alone
      • Johnson Purpose and Source
      • Declare the Glory Curry, Smith, Best
      • Clifford "Across the Pond" Fall 19
      • Oord "Theological Photoessays Fall 19
      • Eyte Cross Cascade "Poem"
    • Summer 2019 Issue >
      • Letter from the Editor Summer 2019
      • Arveson Is There a “Theory of Everything”
      • Anderson The History and Philosophy of Science and Faith
      • Tolsma Science in Church
      • Salviander Black Holes and Atheism
      • Johnson Practical Problems for Literal Adam
      • Hall God and the Assumptions of Scientific Research
      • Linsky Overcoming Misconceptions
      • Wilder Sanctity of Creation
      • Clifford "Across the Pond" Summer19
      • Oord "Theological Photoessays" Summer 2019
      • Flaig Time and Me (Poem)
    • Spring 2019: Creation Care and Environment >
      • Letter from the Editor Spring 2019
      • Bancewicz;Sustainability Pledge: Why the Environment is My Problem
      • Lin; Environmental Problems as a Place for Compromise and Dialogue
      • Garvey; Where the Fall Really Lies
      • Lewis; Solar-Powered Life: Providing Food, Oxygen and Protection
      • Garte; Time and Human Impact on the Environment
      • Mays; Reforming Science Textbooks
      • Carr; Cosmic Energy First, Then Matter: A Spiritual Ethic
      • Kincanon; The Young Earthers and Leibniz
      • Declare the Glory Gauger
      • Clifford "Across the Pond" Spring 2019
      • Oord; Photoessay. Theological Photo Essays
      • Rivera; Photoessay. Digital Artwork: Images of Jesus
      • Albert; Poem. A Goldfish Sings a Tentative Psalm
      • Armstrong; Poem Holy Sonnet XI
    • Winter 2019: Education and Outreach 2 >
      • Letter from the Editor, Winter 2009
      • Applegate; Project Under Construction: Faith Integration Resource for High School Biology
      • LaBelle; Sidewalk Astronomy Evangelism - Taking it to the Streets!
      • Reed; Speaking to the Heart and Mind of Students about Evolution and Creation
      • Marcus; The Conflict Model
      • Rivera; The Implicit Assumptions behind Hitchen's Razor
      • Russo; Redeeming Bias in Discussion of Science and Faith
      • Fischer; Origins, Genesis and Adam
      • Clifford Column, Winter 2019
      • Gait; Photoessay - Stripes
      • Lee; Poem. In Chaos and Nothingness
    • Fall 2018: Education and Outreach 1 >
      • Letter from the Editor Fall 2018
      • Glaze; A Walk within Two Worlds: Faith, Science, and Evolution Advocacy
      • Johnson; Teaching the Controversy in Texas
      • Cootsona; Mere Christianity, Mainstream Science and Emerging Adults
      • Kindstedt; Creating a Third Culture
      • Zeidan; An Effective Way to Integrate Supportive Communication and Christian Belief into Virtual Classrooms
      • Marshall; A New Model of Causation
      • McClure; Nothing in the Bible Makes Sense Except in the Light of Grace
      • Frank; Christianity, Science and Teamwork
      • Assad/Reyes; Interview. Discovering a Renewed Sense of Awe and Wonder about God
      • Clifford Column Fall 2018
      • Menninga; Photoessay. What do These Stones Mean?
    • Summer 2018: Judgment and Peer Review >
      • Letter from the Editors Summer 2018
      • Jones; Peer Review: Avoiding Judgmentalism
      • Arnold; Discovering Spiritual Information Through Peer-Reviewed Science
      • Peterson; Peering at Double-Blind Peer Review
      • Smith; A Philosophical Influence from the Scientific Revolution on Scientific Judgment
      • Mix; The Poetry of Probability
      • Mobley; Randomness vs. the Providence of God?
      • Gordon; Chances are Good: Design and Chance in Genesis 1
      • Siegrist; But the Multiverse...!
      • Reyes; The Community Table: Interview with Marianne Johnson
      • Clifford Column Summer 2018
      • Hill; Poem. Synthesis
      • Lemcio; Poem. I Could See Where This was Going
      • Oord: Photoessay
    • Spring 2018: Chance & Design >
      • Letter from the Editors
      • Bishop; God, Love and Chance
      • Bonham; Quantum Reflections
      • Spaulding; God as Designer
      • Garte; Teleology in Evolution
      • Hall; God, Chance and Buridan's Ox
      • Pohl; Why We Need a Third Culture in Church
      • Dorman; Liturgical Brain
      • Warren; Galapagos
      • Blanchard; On Christian Science
      • Touryan; The Cross as a Cosmic Filter
    • Winter 2018: Race & Inheritance >
      • A Note from the Editors
      • Essay: “Some Pastoral Considerations of CRISPR CAS 9 Gene Editing” by Mario A Russo
      • Essay: “The Genetics and Theology of Race” by Sy Garte
      • Essay: "Grieve the Segregation of Science" by S. Joshua Swamidass
      • Poem: "Cardboard Man" by Ciara Reyes
      • Featured Interview: “Love Is Risk” with Carolyn Finney
      • Essay & Poem: “Abortion Languages: Love, fear, confusion and loss”
      • Essay: "Why the Church Needs Intersectional Feminism" by Emily Herrington
      • Essay: “Elected to Salvation (and other things?)” by Bill Leonard
      • Essay: “Local Colour: A reflection on family, history, and heritage” by Mike Clifford
      • Interview: Corina Newsome, environmentalist and animal keeper
      • Essay: “Spiritual Kin Selection” by Steve Roels
      • Photo Essay: "Trouble in Paradise: Plastic pollution in the Bahamas" by Grace Swing & Robert D Sluka
      • Essay: “Race & Inheritance: Personal reflections and annotations” by Walt Hearn
      • Interview: Carla Ramos, molecular biologist
      • Clifford Column; Discipine Hopping
      • Lemcio; Waves
      • Harris Artwork
      • Hearn; Eulogy - Beyond Science,
    • Summer 17: Cosmology & Theology >
      • Letter from the Editors: Summer 2017
      • Essay: "The News from My Home Galaxy" by Walt Hearn
      • Interview: "Deep Incarnation & the Cosmos: A Conversation with Niels Henrik Gregersen" by Ciara Reyes & Niels Henrik Gregersen
      • Photo Essay: "Breath & Dust" by Kathleen Eady
      • Essay: "Why the Eagle Nebula Just Doesn’t Do It For Me" by Mike Clifford
      • Essay: "The Cosmos in My Hand" by Lucas Mix
      • Interview: “What is Life? On Earth and Beyond” with Andreas Losch
      • Artwork by Missy Pellone
      • Essay: "When God & Science Hide Reality" by Davis Woodworth
      • Essay: "​In Search of Wonder: A Reflection on Reconciling Medieval and Modern Cosmology" by Monica Bennett
      • Essay: "If Christianity and Cosmology Are in Conflict, Whose Side Is Philosophy on?" by Vaughan Rees
    • Winter/Spring 17: "Flesh & Blood" >
      • Letter from the Editor: Winter/Spring 2017
      • Essay: "Probiotics, Prebiotics, Synbiotics: On microbiomes and the meaning of life" by John F. Pohl
      • Essay: "With All Your Mind" by Paul S. Kindsedt
      • Essay: "The Stuff of Life" by Mike Clifford
      • Essay: "Experiencing God’s Love in a Secular Society: A Christian experience with socialized medicine" by Alison Noble
      • Poem: "The Problem with Pain" by Eugne E. Lemcio
      • Essay: "Thoughts of Death in a Cruel World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht and Emily Herrington
      • Essay: "Tissues at Issue" by Walt Hearn
      • Essay: "The Dilemma of Modern Christianity" by Tony Mitchell
      • Poem: "Light" by Billie Holladay Skelley
      • Essay: "Some Theological Implications of Science: Revisiting the Ant" by Mario A. Russo
    • Summer/Fall 16: "Stewardship of Words" >
      • Letter from the Editor: Summer 2016
      • Levity: "Walt Being Walt: Excerpts from the ASA newsletter" by Walt Hearn (compiled by Jack Haas & Emily Ruppel)
      • Poem: "A Prayer Tribute to Walt and Ginny Hearn" by Paul Fayter
      • Essay: "Authentic Science & Authentic Christian Faith" by Paul Arveson
      • Essay: "On Modern-Day Saints & Epistles" by Emily Ruppel
      • Essay: "​Mathematics and the Religious Impulse" by Karl Giberson
      • Poem: "The Wasteful Gene" by Eugne E. Lemcio
      • Three Poems by Dan Eumurian
      • Excerpts from: "The Dictionary of Daily Life in Biblical and Post-Biblical Antiquity" by Edwin Yamauchi
      • Essay: "A Comprehensible Universe: The blessing from God that makes science possible" by Bob Kaita
      • Poem: "The Epistolarian" by Emily Ruppel
    • Spring 16: "Brain Science" >
      • Letter from the Editor: Spring 2016
      • Essay: "Ancient Q, Modern A (?)" by Walt Hearn
      • Essay: "Souls, Brains and People: Who or what are we?" by Gareth D. Jones
      • Essay: "A Functional Theology of Psychopathology" by Edgar Paul Herrington IV
      • Three Poems by Richard Gillum
      • Essay: "Thoughts of Death in an Unkind World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht
      • Short Story: "Malefic" by Jeffrey Allen Mays
      • Essay: "An Engineer Visits a Mindfulness Workshop" by Mike Clifford
      • Essay: "Traces of Trauma in the Body of Christ: The case of The Place of Refuge" by Elizabeth Hernandez
      • Essay: "Did God ‘Create’ Science? Christianity and the uniqueness of the human brain" by William H. Church
    • Winter 16: "Quantum Physics/Epigenetics" >
      • Letter from the Editor: Winter 2016
      • Essay: "God and the New Evolutionary Biology" by Sy Garte
      • Essay: "Quantum Mechanics and the Question of Divine Knowledge" by Stephen J. Robinson
      • Essay: "Creation Out of... Physics?" by Joshua Scott
      • Essay: "Of Books and Bosons" by Mike Clifford
      • Essay: "Words, Words, Words" by Walt Hearn
      • Poem: "Encountering Ernst Haeckel’s 'Ontogeny Recapitulates Phylogeny'" by Eugene Lemcio
      • Essay: "The Extended Evolutionary Synthesis: New conversations and theological questions at the horizons of modern science" by Michael Burdett
      • Poem: "The Difference" by Emily Ruppel
      • Essay: "Maupertuis's Ghost: Finding God in 'action'" by Colin C. Campbell
    • Fall 15: "Technology" >
      • Letter from the Editor: Fall 2015
      • Essay: "‘Braving the New World (Wide Web): Mapping Theological Response to Media" by Justin A. Bailey
      • Poem: "Entropy and Enthalpy" by Glenn R. McGlaughlin
      • Essay: "‘How Proactive Should Christians Be in Learning about Emerging Biomedical Technologies?" by D. Gareth Jones
      • Essay: "‘Can We Fix It? Erm..." by Mike Clifford
      • Poem: "To My Dear Parents" by Sarah Ruden
      • Essay: "‘Which Side, Lord?" by Walt Hearn
      • Poem: "The Column" by John F. Pohl
      • Essay: "‘Technology and the Church" by Derek Schuurman
      • Poem: "On the Shores of Oroumieh" by Emily Ruppel
      • Essay: "‘Technology as Discipline" by Johnny Wei-Bing Lin
    • Summer 15: "Doubt" >
      • Letter from the Editor: Summer 2015
      • Essay: "‘The Road Not Taken’: A personal reflection on careers, counterfactuals and callings" by Tim Middleton
      • Essay: "The Gift of Doubt in My Life" by Rev. Paul Herrington
      • Poem: "The Marsh Birds" by Sarah Ruden
      • Essay: "On St Brendan and the Pendulum of Postgraduate Study" by Mike Clifford
      • Essay: "Doubt: The Invisible Conversation" by Karl W. Giberson
      • Essay: "Doubt, Faith, and Crevasses on My Mind" by Peter M. J. Hess
      • Poem: "Magdalene" by Leonore Wilson
      • Essay: "Breaking Barriers, Ministering in Relationships, and Exemplifying the Gospel" by Stephen Contakes, et al.
      • Poem: "On the Extinction of Matter Near a Black Hole" by Ruth Hoppin
      • Essay: "Sometimes I Doubt..." by Walt Hearn
      • Essay: "The Risks of Love and Life's Big Questions" by Thomas Jay Oord
    • Spring 15: "Animals/Imago Dei" >
      • Letter from the Editor: Spring 2015
      • Essay: "50 Years of Wilderness: a Christian perspective" by Peter van der Burgt
      • Essay: "All Creatures Great and Small " by Walt Hearn
      • Essay: "Let There Be Less: A Christian musing on nature, faith, and farmers’ markets" by Emily Ruppel
      • Poem: "The New Plant and Animal Kingdoms" by Steve Roels
      • Essay: "Of Wonder and Zebrafish" by Ruth Bancewicz
      • Essay: "The Lion, the Spider and the Image of God" by Mike Clifford
      • Cat Poem 1: "Lullaby for Stomp the Cat" by Sarah Ruden
      • Cat Poem 2: "Letting the Dog In" by Emily Ruppel
      • Cat Poem 3: "Reading on the Couch" by Carol Ruppel
      • Essay: "Angry Discussions: A Wrong Way to Stand for Creation Care or Science Advocacy " by Oscar Gonzalez
      • Essay: "Ethical Eating on a Catholic Campus: Some thoughts from a student of environmental studies" by Grace Mican
    • Winter 15: "Information" >
      • Letter from the Editor: Winter 2015
      • Essay: "What Does it Mean to Know?" by Mark Shelhamer
      • Essay: "Knowledge of Information" by Randy Isaac
      • Photo Essay: "Being Here" by Carol Ruppel
      • Essay: "Truth Anyone?" by Walt Hearn
      • Poem: "Transformation" by Ruth Hoppin
      • Interview: "Unpacking Chance, Providence, and the Abraham's Dice Conference" by Olivia Peterson
      • Essay: "On Knowledge and Information–Tales from an English childhood" by Mike Clifford
      • Poem: "Space Travel" by Ruth Hoppin
      • Essay: "Resuming the Science/Faith Conversation" by Jamin Hubner
    • Archives >
      • Past Contributors
      • Fall 14: "History of Science & Christianity" >
        • Letter from the Editor: Fall 2014
        • Essay: "Orchids: Why the founders of modern science cultivated virtue" by Ruth Bancewicz
        • Essay: "Science Falsely So Called: Fundamentalism and Science" by Edward B. Davis
        • Essay: "The Other 'Atom' in Christianity and Science" by Karissa D Carlson
        • Poem: "The Hermit" by Ciara C. Reyes
        • Essay: "Players" by Walt Hearn
        • Essay: "Using Storytelling and Drama in Engineering Lectures" by Mike Clifford
        • Essay: "Is There Anything Historical About Adam and Eve?" by Mike Beidler
        • Essay: "Finding Harmony in Controversy: The early years of the ASA" by Terry Gray and Emily Ruppel
        • Levity: "Fish n' Chips" by Mike Arnold
        • Essay: "Stories" by Walt Hearn
      • Summer 14: "Christian Women in Science" >
        • Letter from the Editor: Summer 2014
        • Essay: "I Really Did That Work: A brief survey of notable Christian Women in Science" by Lynn Billman
        • Essay: "He + She = We" by Walt Hearn
        • Photo Essay: "The Faces of Nature" by Susan Limone
        • Essay: "On Grass that Withers: Overloaded brains and spiritual discernment" by Janet Warren
        • Interview: "Ancient Humans and Modern Choices" with Briana Pobiner
        • Essay: "Crystallographer, Quaker, Pacifist, & Trailblazing Woman of Science: Kathleen Lonsdale’s Christian Life 'Lived Experimentally'” by Kylie Miller and Stephen M. Contakes
        • Artwork: "Eden, Zion" by Harold Sikkema
        • Essay: "Asking the Right Question" by Dorothy Boorse
        • Interview: "Not So Dry Bones" with Mary Schweitzer
        • Essay: "Is Being a Mother and a Scientist Worth It?" by Abby Hodges
        • Essay: "Playing God: A theological reflection on medicine, divine action, and personhood" by Ann Pederson
        • Column: Great Gravity! "BNL 1976 – 2000 (Part 1)"
      • Spring 14: "G&N: The 2-year tour" >
        • Letter from the Editor: Spring 2014
        • Essay: "Political Science?" by Walt Hearn
        • Comic: "Education"
        • Essay: "Finding Hominids with Kamoya Kimeu" by Fred Heeren
        • Poem: "Ziggurat (and Helix)" by Amy Chai
        • Creative Nonfiction: "One Summer" by Dave Harrity
        • Essay: "Do the Heavens Declare the Glory of God?" by Owen Gingerich
        • Comic: "Miracle Mechanics" by Emily Ruppel
        • Essay: "I Sleep A Lot" by Denis O. Lamoureux
        • Poem: "Angels and RNA" by Walt Hearn
        • Comic: "Seminary"
        • Essay: "The Elegance of Antibodies" by Craig M. Story
        • Photo Essay: "Conversing with Nature" by Thomas Jay Oord
        • Essay: "Under the Tutelage of Trees: Arboreal Lessons on Virtue, Kinship, and Integrity" by Peter M. J. Hess
        • Comic: "Humor"
        • Essay: "Science and Scientism in Biology" by Sy Garte
        • Interview: "Biopsychology and Faith" with Heather Looy
      • Winter 14: "Health & Medicine" >
        • Letter from the Editor: Winter 2014
        • Poem: I Have a Piece of Cow in My Heart
        • Essay: Acts of God: Are all mutations random?
        • Column: Beyond Science
        • Poem: Psalm 1859
        • Essay: The Tao of Departing
        • Essay: The Tao of Departing p 2
        • Photo Essay: Walking in Winter
        • Essay: A Christian Doctor on Evolution, Faith, and Suffering
        • Opinion: Making Friends with Frankencorn
        • Poem: Chiaroscuro
        • Interview: "Biopsychology and Faith" with Heather Looy
        • Essay: "The Elegance of Antibodies"
        • Artwork: "Helix" by Harold Sikkema
        • Column: Great Gravity! "Dissertations and Revelations"
      • Fall 13: "Environmentalism" >
        • Letter from the Editor: Fall 2013
        • Poem: Time
        • Essay: Is there Hope for the Ocean?
        • Artwork: "Earthly Tent" by Harold Sikkema
        • Essay: What is Responsible Eating?
        • Essay: Are We Too Obsessed with Food?
        • Poem: Conversation on Creation
        • Essay: Creation Care from the Perspective of a Conservation Geneticist
        • Essay: Mobilizing Scientists for Environmental Missions
        • Poem: Paleocene Spring
        • Interview: Dorothy Boorse
        • Column: Beyond Science
        • Essay: New Testament Motivation for Environmental Stewardship
        • Poem: Stone of House
        • Column: Great Gravity! "Running the Data"
      • Summer 13: "Science & Creativity" >
        • Column: Beyond Science
        • Letter from the Editor: Summer 2013
        • Column: Faith on the Field
        • Poem: Trying Not to Be Too Sunny
        • Comic: "Work in Progress"
        • Essay: Do the Heavens Declare the Glory of God?
        • Essay: Science, Faith, and Creativity
        • Essay: One Summer
        • Comic: "Miracle Mechanics"
        • Featured Essay: Poetry for Scientists
        • Artwork: "Confluence" by Harold Sikkema
        • Column: Great Gravity! "The Great Ungainly Journey West"
      • Spring 13 >
        • Letter from the Editor: Spring 2013
        • Column: Faith on the Field
        • Faith on the Field, cont.
        • Poem: Scientist's Psalm
        • Essay: A Downcast Spirit Dries Up the Bones: More perspectives on depression
        • Artwork: "Lipo Osteo" by Harold Sikkema
        • Feature: The Bible, Evolution, and Grace
        • Column: Beyond Science
        • Book Review: Prisoners of Hope
        • Column: Great Gravity! "The Grad School Years"
      • Winter 13 >
        • Letter from the Editor: Winter 2013
        • Column: Faith on the Field
        • Comic: "Apples to Apples"
        • Creative Nonfiction: "One Winter"
        • Column: Clearing the Middle Path
        • Essay: Science and Scientism in Biology
        • Poem: "Angels and RNA"
        • Feature Article: I Sleep A Lot
        • Poem: "Fragile"
        • Column: Beyond Science
        • CiS 2012 Student Essay Contest: Runner Up
        • Essay: Why Awe?
        • CiS 2012 Student Essay Contest: First Place
        • Column: Great Gravity! "A Bit of Perspective"
        • Column: Modern Frontiers, Ancient Faith
        • Column: Time Capsule
      • Fall 12 >
        • Letter from the Editor: Fall 2012
        • The Director's Corner
        • Column: Faith on the Field
        • Comic: "Education"
        • Interview: Greetings from Mars!
        • Column: Clearing the Middle Path
        • Photo Essay: "Conversing with Nature"
        • Comic: "Abe"
        • Essay: Evolution and Imago Dei
        • Poem: "Locus Iste"
        • Levity: Beyond Science
        • Essay: God, Occam, and Science
        • Opinion: Humility and Grace
        • Levity: Great Gravity! "The College Years"
        • Poem: "Q.E.D."
        • Essay: My Overlapping Magisteria
        • Column: Time Capsule
      • Summer 12 >
        • Table of Contents
        • Letter from the Editor: Summer 2012
        • Director's Corner
        • Column: Faith on the Field
        • Column: Modern Frontiers, Ancient Faith
        • Comic: "Seminary"
        • Poem: "Temptation in the Wired Wilderness"
        • Levity: Beyond Science
        • Opinion: "The Breaking Bread"
        • Comic: "Humor"
        • Column: Clearing the Middle Path
        • Poem: "Ziggurat (and Helix)"
        • Levity: Great Gravity! "The Grade School Years"
        • Opinion: "Adam and the Origin of Man"
        • Poem: "Missa Solemnis"
        • Column: Time Capsule
      • Spring 12 >
        • Table of Contents
        • Letter from the Editor: Spring 2012
        • Director's corner
        • Column: Faith on the Field
        • Column: Time Capsule
        • Poem: "From Where do We Come?"
        • Featured Scientist
        • Levity: Beyond Science
        • Essay: "Faith and Science"
        • Fiction: "A Matter of Dust"
        • Levity: Great Gravity! "The Early Years"
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God and Nature ​                                                                                Spring 2023


Comments on the Implications of Assembly Theory for Origin of Life

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By Larry Funck 

The primary question raised by Sy Garte in his article on assembly theory in the Winter 2023 issue of God and Nature involves its relevance to the question of the origin of life. Garte’s article reflects on the results of a recent paper in Nature about using an index of molecular complexity (which the authors called the Molecular Assembly, or MA, index) as a way to detect life in distant worlds. I was curious if there were other comments in the literature regarding possible implications of assembly theory for the origin-of-life question, so I checked Web of Science to find citations for this Nature paper. I have discovered that essentially all of them were in articles related to exploratory astrobiology.

The one exception was a “Perspective” article in Life entitled “The Grayness of the Origin of Life” by Smith, Hillary H. et al. (1). The emphasis in this article is on the severe challenges that arise from the numerous unknowns inherent in the origin of life. Among these is the definition of the phenomenon itself. What is life? Is there a threshold that would provide criteria for distinguishing between a system  classified as abiotic and one classified as biotic? The authors’ answer is in the negative. Instead, they suggest a gradual progression between the non-living and the living resulting from the “protracted evolutionary process that gave rise to life” (2). They describe the progression from abiotic to biotic, or geochemistry to biochemistry, as involving a spectrum over time with no clear distinctions, but rather a lot of “grayness.”

The high MA values of biotic molecules may be interpreted as another indication of how extraordinarily life-friendly this Creation is.
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Smith et al.’s approach draws upon the “chemoton” model of Gánti to provide a minimal model of life, comprising the three fundamental subsystem functions—compartmentalization, metabolism, and an information system for reproduction (3). Interestingly, their reference to the Nature paper occurs in the context of a discussion about the requirements for information storage via RNA, where they make the point that “the ability to store useful information is determined by the length of the encoding string coupled with maintenance of non-random sequences selected by evolution over time” (4). They relate assembly theory to the origin-of-life question in the context of the origin of information storage and transmission, but do not draw any direct conclusions from the theory.

In my opinion the critical juncture between assembly theory and origin of life involves the fundamental question of the probability of life’s occurrence. As Garte suggests in his article, molecules with a higher molecular assembly (MA) index, especially the critically important nucleotides and their polymers, molecules involved in information storage and transmission, would be hard to produce abiotically.

I would suppose that assembly theory proponents would argue that there is an inverse correspondence between a molecule’s MA value and the probability of that molecule occurring in the absence of life. I suspect that they would want to leave open the question of the probability of the origin of life itself.

If the production of high MA molecules needed for life’s origin had to occur in advance of its origin, then it would follow that life’s spontaneous appearance would have an exceedingly low probability. But what if life  emerged through a “protracted evolutionary process” that also produced the high MA molecules as part of that process? Then both living systems and high MA molecules associated with life would be the outcome of life’s origin. The question boils down to this: What were the chemical pathways to the production of systems possessing high MA molecules—systems capable of exhibiting life-like behavior, and therefore classifiable as biotic—or, in simpler terms, how did life begin?    

Origin-of-life theoretician Stuart Kauffman wrote in 1995 (still true today): “Anyone who tells you that he or she knows how life started on the sere earth… is a fool or a knave” (5).

Origin-of-life theories are abundant and varied. For example, there are the geneticists versus the metabolists. Which had primacy—the production of energy/metabolites or the origin of information coding and reproductive capability? What constituted the first forms of life, and what did they eat—were they heterotrophic, incorporating  organic substances, or were they autotrophs, making their own organics from inorganic starting materials in their initial formation and their continued maintenance?

One of the suggested ways that a geochemical to biochemical transition is imagined involves the proposal of catalytic activity by metal atoms/ions on mineral surfaces that initiated the first versions of metabolic processes and led to the development of metalloenzymes. There are plenty of examples of speculative theory along these lines, most extensively in the proposals for life’s origin at deep sea hydrothermal vents.

Perhaps the best experimental support of an origin via autotrophic metabolism comes from recent discoveries of non-enzymatic metabolism. Markus Ralser details in his 2018 review article (6) multiple examples discovered within the last decade of entire metabolic pathways catalyzed by metal ions, particularly Fe(II). He argues that this provides substantial support for the idea that biochemical pathways originated in an abiotic, geochemical context. Ralser suggests that by the use of appropriate analytical techniques, it is likely that many more examples of non-enzymatic metabolic pathways will be discovered.

Muchowska, et al., in a more recent review article (7), discuss  the concepts advanced by Ralser and extend the consideration to the possibility of non-enzymatic synthesis pathways for nucleotides that would parallel their biosynthetic pathways. They suggest that the lack of current evidence for such pathways is likely a consequence of the lack of research along those lines. They also argue in favor of a “systems” approach to prebiotic chemistry, which would investigate the possibility of cooperative development of nucleic acids and polypeptides.

So how does this relate to the question of high MA molecules before life’s emergence? In short, the occurrence of complex metabolic pathways driven not by high MA enzymes but by very low MA metal ions suggests the possibility that the high MA molecules may have emerged in the process of the gradual progression towards systems that would have increasingly biotic characteristics and be eventually characterized as alive.

Arguably the most critical step in the progression towards life involved the appearance of the genetic coding system and accompanying enzymatic apparatus. There are several theories about how this occurred, but none has gained wide acceptance to date. In my opinion, the most attractive one has been advanced by Carter and Wills (8). Their theory, which is empirically based, rests principally on a proposal of intimate cooperation between RNA and peptides in the emergence of the code through the formation of “complexes involving structurally complementary oligonucleotides and dipeptides” (9). These complexes are proposed to have originated long before genuine code expression occurred involving simple versions of tRNA and aaRS proteins.

My guess is that were Carter or Wills to be asked about the existence of these relatively high MA value molecular complexes well in advance of a functional coding system, they would probably reply in a manner similar to that proposed above—the high MA oligonucleotide/dipeptide complexes were merely intermediates on the path to life in the “protracted evolutionary process.”
So what should we conclude? Should the high MA values for biomolecules be viewed as problematic for the origin-of-life theoretician? I would suggest they will be troublesome if the theoretician is uncomfortable living in a scientific world of extreme uncertainty (or, should I say, a very gray world?).

As a theist who is comfortable accepting the proposals of modern cosmology about the history of the universe—that the sun, moon, stars and this earth came into being via a process—I am inclined to expect that God brought life into existence on this earth in a similar fashion. How it happened in scientific terms remains a deep, deep mystery. An easy way out, it would seem, might be to simply agree with those who just proclaim it to be a miracle and let it go at that. I would prefer an alternative response. The high MA values of biotic molecules may be interpreted as another indication of how extraordinarily life-friendly this Creation is.

Much has been written and argued about the fine-tuning of our universe. Perhaps we could view the existence of living systems that employ low-probability high MA molecules for their existence as an indication that the entire chemical space that gave rise to this phenomenon called life was masterfully intended (designed?) by the Creator to ensure life’s occurrence, though the process leading to it may seem to us to be very gray indeed. This would be fine-tuning of chemistry on a grand scale.
 
References

1. Smith, Hillary H., et al. “The Grayness of the Origin of Life.” Life 11, 498, 2021.
2. Ibid.
3. Gánti, T. “Biogenesis Itself.” J. Theor. Biol. 187, 583-593, 1997.
4.  Smith, et al.
5. Kauffman, Stuart. At Home in the Universe: The Search for the Laws of Self-Organization and Complexity. (New York: Oxford Press, 1995) 31.
6. Ralser, Markus. “An Appeal to Magic? The Discovery of a Non-enzymatic Metabolism and Its Role in the Origins of Life.” Biochemical Journal 475, 2577-2592, 2018.
7.  Muchowska, Kamila B., et al. “Nonenzymatic Metabolic Reactions and Life’s Origins.” Chem. Rev. 120, 7708-7744, 2020.
8.  Carter, Charles W., Jr. and Wills, Peter R. “The Roots of Genetic Coding in Aminoacyl-tRNA Synthetase Duality.” Annual Review of Biochemistry 90, 349-373, 2021.
9.  Carter, Charles W., Jr. “What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental Attention.” Life 5, 294-320, 2015.
 
Larry Funck has a B.S. in Chemistry from Lebanon Valley College, (1964), and a Ph.D. in Inorganic Chemistry from Lehigh University, (1969). He was a Professor of Inorganic Chemistry at Wheaton College (IL), from 1969-2011; a Fulbright Fellow, at the National University of Lesotho, 1995-96. Dr. Funck is currently Emeritus Professor, Wheaton College, and adjunct Professor teaching Origin of Life component of Scientific Theories of Origins course at Wheaton. He is coauthor of Understanding Scientific Theories of Origins, IVP, (2018).

God & Nature magazine is a publication of the American Scientific Affiliation, an international network of Christians in science: www.asa3.org