God & Nature Magazine
  • Spring 2022 Issue
    • Letter from the Editors Spring 2022
    • Curry, Knowldege and Truth
    • Pinkham, On a Car Emblem
    • Murray, Candling the Egg
    • Carr, Music, Math, Religion
    • Smith, Wonder and Longing
    • Linsky, Cyber Service
    • Bostrom, Buteo
    • Obi, Coincidences
  • Winter 2022 Issue
    • Garte &Albert Letter Winter 2022
    • Thuraisingham Pondering Invisible
    • Cornwell Mediations from Molecular Biologist
    • Fagunwa Blsck Scientist & Church Father
    • Garte A Dialogue
    • Gonzalez Being Human
    • Klein Naturalist in Two Worlds
    • Bostrom Creeds
    • Clifford Winter 2022
    • Ardern Contact Points
    • Cooper Imagine No Christmas
  • Fall 2021 Issue
    • Garte &Albert Letter Fall2021
    • Johnson, God Winks
    • Cottraux, Ancient Aliens
    • Arveson, Anti-Vax Email
    • Gammon, Evolutionary Insights
    • Mitchell, No One Told Me
    • Rummo, Faith in the Invisible
    • Bostrom, Fall Furrows
    • Lemcio, A Franciscan Weekend
    • Funk, Plant Haiku
    • Robinson & Lim, Who is God?
  • Past Issues
    • Summer 2021 Issue >
      • Garte &Albert Letter Sum2021
      • Warren, Immunization and Salvation
      • Defoe, Bernard Ramm
      • Cornwell Canine to Divine
      • Mix, Running with Nature
      • Pinkham, Scuba Divers
      • Cao, Physics and Bible
      • Bostrom, Sugar Birds
      • Clifford Sum21
      • Oostema, Evolution of Faith
      • Hall, Generation upon Generation
    • Spring 2021 Issue >
      • Garte and Albert Letter Spring 2021
      • Loikanen, Divine Action
      • Madison, Humus and Humility
      • Lappin, Puddles and Persons
      • Cornwell, God's GPS
      • Touryan, Contolled Fusion
      • Russo, Vaccine and Salvation
      • Bostrom, Short-eared Owl
      • Redkoles, Expect Unexpected
      • Clifford, Boring
      • McFarland, Imposition of Carbon
      • Lemcio, Manis Mastodon
    • Winter 2021 Issue >
      • Winter 2021 Contents >
        • Garte and Albert Letter from the Editors
        • Burnett How iit All Started
        • Isaac Director's Corner
        • Ruppel Herrington, First Editor
        • Burnett Origin of Lire
        • Hearn Balance
        • Middleton Natural Theology
        • Story Antibodies and Randomness
        • Lamoureux I Sleep a Lot
        • Warren Overloaded Brains
        • Isaac Knowledge of Information
        • Bancewicz Wonder and Zebrafish
        • Oord Photoessay
        • Albert Hope in Winter
        • Clifford Storytelling & Drama in Teaching
        • Pohl The Column (Poetry)
    • Fall 2020 Issue >
      • Letter from Editors
      • Pohl, Panpsychism and Microbiome
      • Reyes, Communion During Loss
      • Griffin, Hands On
      • Azarvan, Science and Limits
      • Cornwell, Search Engines for God
      • Thuraisingham, Duality of Humans and Particles
      • Touryan, Prayers of Petition
      • George, Perfect Vision
      • Declare the Glory, Green: Awe
      • Bostrom Purpose
      • Oord, Theological Photoessay
      • Clifford, Food, Water, Waste
    • Summer 2020 Issue >
      • Summer 2020 Contents >
        • Editors Letter Summer2020
        • Jones, Science Faith Duopoly
        • Mix, God and the Virus
        • Warner, COVID-19 and Goodness of Creation
        • Gonzalez, Pandemic and Groaning of Creation
        • Johnson, Star Wars Food
        • Pyle, It Takes a (Medical ) Village
        • Arveson, Use for 3D Printers
        • Peterson, Pandemic and Research
        • Zeidan, Mentorship Online
        • Oleskeiwicz, Dragonfly on Water
        • Carr, COVID-19 and Climate Change
        • Nierrman, The Squirrel
        • Cornwell, COVIS-19 Bucket List
        • Bostrom, Grass Thoughts
        • Clifford, Summ20 Conflict
    • Spring 2020 Issue >
      • Letter from the Editors SP20
      • AD
      • Murphy, Nature and Calvary
      • Dickin, The Flood and Genesis 1
      • Gruenberg, Empiricism and Christian Spirituality
      • Ungureanu, Science, Religion, Protestant Tradition
      • Russo, How does it End?
      • Siegrist, Problems with Materialism
      • Ohlman, 20/20 in 2020
      • Warren, Rock Frogs
      • Edwards, Sanctuary
      • Bostrom, Clothed
      • Clifford, The Lent of Lockdown Spring 2020
      • Hall, 1:30 AM on a Tuesday (Poem)
    • Winter 2020 Issue >
      • Letter from the Editor Winter 2020
      • AD
      • Wimberly Inheritance, Meaning and Code
      • Defoe; A Pastor's Journey
      • Mix The Ends of the World
      • Pevarnik Limits of Physics
      • Greenberg "Godly" Science
      • Pinkham Teleological Thinking
      • Alexanian How to Witness
      • "Declare the Glory" Neal, Cross, Gait
      • Clifford "Across the Pond" Winter 2020
      • Oord "Theological Photoessays" Winter 2020
      • Salviander The Objective Man (Poem)
      • Ohlman Orphan of the Universe (Poem)
      • Lemcio Grey's Anatomy (Poem)
    • Fall 2019 Issue >
      • Letter from the Editor Fall 2019
      • Phillippy Mathematics and God
      • Pohl & Thoelen Databases
      • Garte Limits of Science
      • Mitroka Healthy Lifestyle
      • Sigmon Science and Revelation
      • Mariani Compatibility Creation and Evolution
      • Anders Theistic Evolution
      • Touryan Are we alone
      • Johnson Purpose and Source
      • Declare the Glory Curry, Smith, Best
      • Clifford "Across the Pond" Fall 19
      • Oord "Theological Photoessays Fall 19
      • Eyte Cross Cascade "Poem"
    • Summer 2019 Issue >
      • Letter from the Editor Summer 2019
      • Arveson Is There a “Theory of Everything”
      • Anderson The History and Philosophy of Science and Faith
      • Tolsma Science in Church
      • Salviander Black Holes and Atheism
      • Johnson Practical Problems for Literal Adam
      • Hall God and the Assumptions of Scientific Research
      • Linsky Overcoming Misconceptions
      • Wilder Sanctity of Creation
      • Clifford "Across the Pond" Summer19
      • Oord "Theological Photoessays" Summer 2019
      • Flaig Time and Me (Poem)
    • Spring 2019: Creation Care and Environment >
      • Letter from the Editor Spring 2019
      • Bancewicz;Sustainability Pledge: Why the Environment is My Problem
      • Lin; Environmental Problems as a Place for Compromise and Dialogue
      • Garvey; Where the Fall Really Lies
      • Lewis; Solar-Powered Life: Providing Food, Oxygen and Protection
      • Garte; Time and Human Impact on the Environment
      • Mays; Reforming Science Textbooks
      • Carr; Cosmic Energy First, Then Matter: A Spiritual Ethic
      • Kincanon; The Young Earthers and Leibniz
      • Declare the Glory Gauger
      • Clifford "Across the Pond" Spring 2019
      • Oord; Photoessay. Theological Photo Essays
      • Rivera; Photoessay. Digital Artwork: Images of Jesus
      • Albert; Poem. A Goldfish Sings a Tentative Psalm
      • Armstrong; Poem Holy Sonnet XI
    • Winter 2019: Education and Outreach 2 >
      • Letter from the Editor, Winter 2009
      • Applegate; Project Under Construction: Faith Integration Resource for High School Biology
      • LaBelle; Sidewalk Astronomy Evangelism - Taking it to the Streets!
      • Reed; Speaking to the Heart and Mind of Students about Evolution and Creation
      • Marcus; The Conflict Model
      • Rivera; The Implicit Assumptions behind Hitchen's Razor
      • Russo; Redeeming Bias in Discussion of Science and Faith
      • Fischer; Origins, Genesis and Adam
      • Clifford Column, Winter 2019
      • Gait; Photoessay - Stripes
      • Lee; Poem. In Chaos and Nothingness
    • Fall 2018: Education and Outreach 1 >
      • Letter from the Editor Fall 2018
      • Glaze; A Walk within Two Worlds: Faith, Science, and Evolution Advocacy
      • Johnson; Teaching the Controversy in Texas
      • Cootsona; Mere Christianity, Mainstream Science and Emerging Adults
      • Kindstedt; Creating a Third Culture
      • Zeidan; An Effective Way to Integrate Supportive Communication and Christian Belief into Virtual Classrooms
      • Marshall; A New Model of Causation
      • McClure; Nothing in the Bible Makes Sense Except in the Light of Grace
      • Frank; Christianity, Science and Teamwork
      • Assad/Reyes; Interview. Discovering a Renewed Sense of Awe and Wonder about God
      • Clifford Column Fall 2018
      • Menninga; Photoessay. What do These Stones Mean?
    • Summer 2018: Judgment and Peer Review >
      • Letter from the Editors Summer 2018
      • Jones; Peer Review: Avoiding Judgmentalism
      • Arnold; Discovering Spiritual Information Through Peer-Reviewed Science
      • Peterson; Peering at Double-Blind Peer Review
      • Smith; A Philosophical Influence from the Scientific Revolution on Scientific Judgment
      • Mix; The Poetry of Probability
      • Mobley; Randomness vs. the Providence of God?
      • Gordon; Chances are Good: Design and Chance in Genesis 1
      • Siegrist; But the Multiverse...!
      • Reyes; The Community Table: Interview with Marianne Johnson
      • Clifford Column Summer 2018
      • Hill; Poem. Synthesis
      • Lemcio; Poem. I Could See Where This was Going
      • Oord: Photoessay
    • Spring 2018: Chance & Design >
      • Letter from the Editors
      • Bishop; God, Love and Chance
      • Bonham; Quantum Reflections
      • Spaulding; God as Designer
      • Garte; Teleology in Evolution
      • Hall; God, Chance and Buridan's Ox
      • Pohl; Why We Need a Third Culture in Church
      • Dorman; Liturgical Brain
      • Warren; Galapagos
      • Blanchard; On Christian Science
      • Touryan; The Cross as a Cosmic Filter
    • Winter 2018: Race & Inheritance >
      • A Note from the Editors
      • Essay: “Some Pastoral Considerations of CRISPR CAS 9 Gene Editing” by Mario A Russo
      • Essay: “The Genetics and Theology of Race” by Sy Garte
      • Essay: "Grieve the Segregation of Science" by S. Joshua Swamidass
      • Poem: "Cardboard Man" by Ciara Reyes
      • Featured Interview: “Love Is Risk” with Carolyn Finney
      • Essay & Poem: “Abortion Languages: Love, fear, confusion and loss”
      • Essay: "Why the Church Needs Intersectional Feminism" by Emily Herrington
      • Essay: “Elected to Salvation (and other things?)” by Bill Leonard
      • Essay: “Local Colour: A reflection on family, history, and heritage” by Mike Clifford
      • Interview: Corina Newsome, environmentalist and animal keeper
      • Essay: “Spiritual Kin Selection” by Steve Roels
      • Photo Essay: "Trouble in Paradise: Plastic pollution in the Bahamas" by Grace Swing & Robert D Sluka
      • Essay: “Race & Inheritance: Personal reflections and annotations” by Walt Hearn
      • Interview: Carla Ramos, molecular biologist
      • Clifford Column; Discipine Hopping
      • Lemcio; Waves
      • Harris Artwork
      • Hearn; Eulogy - Beyond Science,
    • Summer 17: Cosmology & Theology >
      • Letter from the Editors: Summer 2017
      • Essay: "The News from My Home Galaxy" by Walt Hearn
      • Interview: "Deep Incarnation & the Cosmos: A Conversation with Niels Henrik Gregersen" by Ciara Reyes & Niels Henrik Gregersen
      • Photo Essay: "Breath & Dust" by Kathleen Eady
      • Essay: "Why the Eagle Nebula Just Doesn’t Do It For Me" by Mike Clifford
      • Essay: "The Cosmos in My Hand" by Lucas Mix
      • Interview: “What is Life? On Earth and Beyond” with Andreas Losch
      • Artwork by Missy Pellone
      • Essay: "When God & Science Hide Reality" by Davis Woodworth
      • Essay: "​In Search of Wonder: A Reflection on Reconciling Medieval and Modern Cosmology" by Monica Bennett
      • Essay: "If Christianity and Cosmology Are in Conflict, Whose Side Is Philosophy on?" by Vaughan Rees
    • Winter/Spring 17: "Flesh & Blood" >
      • Letter from the Editor: Winter/Spring 2017
      • Essay: "Probiotics, Prebiotics, Synbiotics: On microbiomes and the meaning of life" by John F. Pohl
      • Essay: "With All Your Mind" by Paul S. Kindsedt
      • Essay: "The Stuff of Life" by Mike Clifford
      • Essay: "Experiencing God’s Love in a Secular Society: A Christian experience with socialized medicine" by Alison Noble
      • Poem: "The Problem with Pain" by Eugne E. Lemcio
      • Essay: "Thoughts of Death in a Cruel World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht and Emily Herrington
      • Essay: "Tissues at Issue" by Walt Hearn
      • Essay: "The Dilemma of Modern Christianity" by Tony Mitchell
      • Poem: "Light" by Billie Holladay Skelley
      • Essay: "Some Theological Implications of Science: Revisiting the Ant" by Mario A. Russo
    • Summer/Fall 16: "Stewardship of Words" >
      • Letter from the Editor: Summer 2016
      • Levity: "Walt Being Walt: Excerpts from the ASA newsletter" by Walt Hearn (compiled by Jack Haas & Emily Ruppel)
      • Poem: "A Prayer Tribute to Walt and Ginny Hearn" by Paul Fayter
      • Essay: "Authentic Science & Authentic Christian Faith" by Paul Arveson
      • Essay: "On Modern-Day Saints & Epistles" by Emily Ruppel
      • Essay: "​Mathematics and the Religious Impulse" by Karl Giberson
      • Poem: "The Wasteful Gene" by Eugne E. Lemcio
      • Three Poems by Dan Eumurian
      • Excerpts from: "The Dictionary of Daily Life in Biblical and Post-Biblical Antiquity" by Edwin Yamauchi
      • Essay: "A Comprehensible Universe: The blessing from God that makes science possible" by Bob Kaita
      • Poem: "The Epistolarian" by Emily Ruppel
    • Spring 16: "Brain Science" >
      • Letter from the Editor: Spring 2016
      • Essay: "Ancient Q, Modern A (?)" by Walt Hearn
      • Essay: "Souls, Brains and People: Who or what are we?" by Gareth D. Jones
      • Essay: "A Functional Theology of Psychopathology" by Edgar Paul Herrington IV
      • Three Poems by Richard Gillum
      • Essay: "Thoughts of Death in an Unkind World: Job’s suicidal ideation and the “right” Christian response to depression" by Jennifer Michael Hecht
      • Short Story: "Malefic" by Jeffrey Allen Mays
      • Essay: "An Engineer Visits a Mindfulness Workshop" by Mike Clifford
      • Essay: "Traces of Trauma in the Body of Christ: The case of The Place of Refuge" by Elizabeth Hernandez
      • Essay: "Did God ‘Create’ Science? Christianity and the uniqueness of the human brain" by William H. Church
    • Winter 16: "Quantum Physics/Epigenetics" >
      • Letter from the Editor: Winter 2016
      • Essay: "God and the New Evolutionary Biology" by Sy Garte
      • Essay: "Quantum Mechanics and the Question of Divine Knowledge" by Stephen J. Robinson
      • Essay: "Creation Out of... Physics?" by Joshua Scott
      • Essay: "Of Books and Bosons" by Mike Clifford
      • Essay: "Words, Words, Words" by Walt Hearn
      • Poem: "Encountering Ernst Haeckel’s 'Ontogeny Recapitulates Phylogeny'" by Eugene Lemcio
      • Essay: "The Extended Evolutionary Synthesis: New conversations and theological questions at the horizons of modern science" by Michael Burdett
      • Poem: "The Difference" by Emily Ruppel
      • Essay: "Maupertuis's Ghost: Finding God in 'action'" by Colin C. Campbell
    • Fall 15: "Technology" >
      • Letter from the Editor: Fall 2015
      • Essay: "‘Braving the New World (Wide Web): Mapping Theological Response to Media" by Justin A. Bailey
      • Poem: "Entropy and Enthalpy" by Glenn R. McGlaughlin
      • Essay: "‘How Proactive Should Christians Be in Learning about Emerging Biomedical Technologies?" by D. Gareth Jones
      • Essay: "‘Can We Fix It? Erm..." by Mike Clifford
      • Poem: "To My Dear Parents" by Sarah Ruden
      • Essay: "‘Which Side, Lord?" by Walt Hearn
      • Poem: "The Column" by John F. Pohl
      • Essay: "‘Technology and the Church" by Derek Schuurman
      • Poem: "On the Shores of Oroumieh" by Emily Ruppel
      • Essay: "‘Technology as Discipline" by Johnny Wei-Bing Lin
    • Summer 15: "Doubt" >
      • Letter from the Editor: Summer 2015
      • Essay: "‘The Road Not Taken’: A personal reflection on careers, counterfactuals and callings" by Tim Middleton
      • Essay: "The Gift of Doubt in My Life" by Rev. Paul Herrington
      • Poem: "The Marsh Birds" by Sarah Ruden
      • Essay: "On St Brendan and the Pendulum of Postgraduate Study" by Mike Clifford
      • Essay: "Doubt: The Invisible Conversation" by Karl W. Giberson
      • Essay: "Doubt, Faith, and Crevasses on My Mind" by Peter M. J. Hess
      • Poem: "Magdalene" by Leonore Wilson
      • Essay: "Breaking Barriers, Ministering in Relationships, and Exemplifying the Gospel" by Stephen Contakes, et al.
      • Poem: "On the Extinction of Matter Near a Black Hole" by Ruth Hoppin
      • Essay: "Sometimes I Doubt..." by Walt Hearn
      • Essay: "The Risks of Love and Life's Big Questions" by Thomas Jay Oord
    • Spring 15: "Animals/Imago Dei" >
      • Letter from the Editor: Spring 2015
      • Essay: "50 Years of Wilderness: a Christian perspective" by Peter van der Burgt
      • Essay: "All Creatures Great and Small " by Walt Hearn
      • Essay: "Let There Be Less: A Christian musing on nature, faith, and farmers’ markets" by Emily Ruppel
      • Poem: "The New Plant and Animal Kingdoms" by Steve Roels
      • Essay: "Of Wonder and Zebrafish" by Ruth Bancewicz
      • Essay: "The Lion, the Spider and the Image of God" by Mike Clifford
      • Cat Poem 1: "Lullaby for Stomp the Cat" by Sarah Ruden
      • Cat Poem 2: "Letting the Dog In" by Emily Ruppel
      • Cat Poem 3: "Reading on the Couch" by Carol Ruppel
      • Essay: "Angry Discussions: A Wrong Way to Stand for Creation Care or Science Advocacy " by Oscar Gonzalez
      • Essay: "Ethical Eating on a Catholic Campus: Some thoughts from a student of environmental studies" by Grace Mican
    • Winter 15: "Information" >
      • Letter from the Editor: Winter 2015
      • Essay: "What Does it Mean to Know?" by Mark Shelhamer
      • Essay: "Knowledge of Information" by Randy Isaac
      • Photo Essay: "Being Here" by Carol Ruppel
      • Essay: "Truth Anyone?" by Walt Hearn
      • Poem: "Transformation" by Ruth Hoppin
      • Interview: "Unpacking Chance, Providence, and the Abraham's Dice Conference" by Olivia Peterson
      • Essay: "On Knowledge and Information–Tales from an English childhood" by Mike Clifford
      • Poem: "Space Travel" by Ruth Hoppin
      • Essay: "Resuming the Science/Faith Conversation" by Jamin Hubner
    • Archives >
      • Past Contributors
      • Unpublished Materal >
        • Richard Graven A Vision of God
      • Fall 14: "History of Science & Christianity" >
        • Letter from the Editor: Fall 2014
        • Essay: "Orchids: Why the founders of modern science cultivated virtue" by Ruth Bancewicz
        • Essay: "Science Falsely So Called: Fundamentalism and Science" by Edward B. Davis
        • Essay: "The Other 'Atom' in Christianity and Science" by Karissa D Carlson
        • Poem: "The Hermit" by Ciara C. Reyes
        • Essay: "Players" by Walt Hearn
        • Essay: "Using Storytelling and Drama in Engineering Lectures" by Mike Clifford
        • Essay: "Is There Anything Historical About Adam and Eve?" by Mike Beidler
        • Essay: "Finding Harmony in Controversy: The early years of the ASA" by Terry Gray and Emily Ruppel
        • Levity: "Fish n' Chips" by Mike Arnold
        • Essay: "Stories" by Walt Hearn
      • Summer 14: "Christian Women in Science" >
        • Letter from the Editor: Summer 2014
        • Essay: "I Really Did That Work: A brief survey of notable Christian Women in Science" by Lynn Billman
        • Essay: "He + She = We" by Walt Hearn
        • Photo Essay: "The Faces of Nature" by Susan Limone
        • Essay: "On Grass that Withers: Overloaded brains and spiritual discernment" by Janet Warren
        • Interview: "Ancient Humans and Modern Choices" with Briana Pobiner
        • Essay: "Crystallographer, Quaker, Pacifist, & Trailblazing Woman of Science: Kathleen Lonsdale’s Christian Life 'Lived Experimentally'” by Kylie Miller and Stephen M. Contakes
        • Artwork: "Eden, Zion" by Harold Sikkema
        • Essay: "Asking the Right Question" by Dorothy Boorse
        • Interview: "Not So Dry Bones" with Mary Schweitzer
        • Essay: "Is Being a Mother and a Scientist Worth It?" by Abby Hodges
        • Essay: "Playing God: A theological reflection on medicine, divine action, and personhood" by Ann Pederson
        • Column: Great Gravity! "BNL 1976 – 2000 (Part 1)"
      • Spring 14: "G&N: The 2-year tour" >
        • Letter from the Editor: Spring 2014
        • Essay: "Political Science?" by Walt Hearn
        • Comic: "Education"
        • Essay: "Finding Hominids with Kamoya Kimeu" by Fred Heeren
        • Poem: "Ziggurat (and Helix)" by Amy Chai
        • Creative Nonfiction: "One Summer" by Dave Harrity
        • Essay: "Do the Heavens Declare the Glory of God?" by Owen Gingerich
        • Comic: "Miracle Mechanics" by Emily Ruppel
        • Essay: "I Sleep A Lot" by Denis O. Lamoureux
        • Poem: "Angels and RNA" by Walt Hearn
        • Comic: "Seminary"
        • Essay: "The Elegance of Antibodies" by Craig M. Story
        • Photo Essay: "Conversing with Nature" by Thomas Jay Oord
        • Essay: "Under the Tutelage of Trees: Arboreal Lessons on Virtue, Kinship, and Integrity" by Peter M. J. Hess
        • Comic: "Humor"
        • Essay: "Science and Scientism in Biology" by Sy Garte
        • Interview: "Biopsychology and Faith" with Heather Looy
      • Winter 14: "Health & Medicine" >
        • Letter from the Editor: Winter 2014
        • Poem: I Have a Piece of Cow in My Heart
        • Essay: Acts of God: Are all mutations random?
        • Column: Beyond Science
        • Poem: Psalm 1859
        • Essay: The Tao of Departing
        • Essay: The Tao of Departing p 2
        • Photo Essay: Walking in Winter
        • Essay: A Christian Doctor on Evolution, Faith, and Suffering
        • Opinion: Making Friends with Frankencorn
        • Poem: Chiaroscuro
        • Interview: "Biopsychology and Faith" with Heather Looy
        • Essay: "The Elegance of Antibodies"
        • Artwork: "Helix" by Harold Sikkema
        • Column: Great Gravity! "Dissertations and Revelations"
      • Fall 13: "Environmentalism" >
        • Letter from the Editor: Fall 2013
        • Poem: Time
        • Essay: Is there Hope for the Ocean?
        • Artwork: "Earthly Tent" by Harold Sikkema
        • Essay: What is Responsible Eating?
        • Essay: Are We Too Obsessed with Food?
        • Poem: Conversation on Creation
        • Essay: Creation Care from the Perspective of a Conservation Geneticist
        • Essay: Mobilizing Scientists for Environmental Missions
        • Poem: Paleocene Spring
        • Interview: Dorothy Boorse
        • Column: Beyond Science
        • Essay: New Testament Motivation for Environmental Stewardship
        • Poem: Stone of House
        • Column: Great Gravity! "Running the Data"
      • Summer 13: "Science & Creativity" >
        • Column: Beyond Science
        • Letter from the Editor: Summer 2013
        • Column: Faith on the Field
        • Poem: Trying Not to Be Too Sunny
        • Comic: "Work in Progress"
        • Essay: Do the Heavens Declare the Glory of God?
        • Essay: Science, Faith, and Creativity
        • Essay: One Summer
        • Comic: "Miracle Mechanics"
        • Featured Essay: Poetry for Scientists
        • Artwork: "Confluence" by Harold Sikkema
        • Column: Great Gravity! "The Great Ungainly Journey West"
      • Winter 13 >
        • Letter from the Editor: Winter 2013
        • Column: Faith on the Field
        • Comic: "Apples to Apples"
        • Creative Nonfiction: "One Winter"
        • Column: Clearing the Middle Path
        • Essay: Science and Scientism in Biology
        • Poem: "Angels and RNA"
        • Feature Article: I Sleep A Lot
        • Poem: "Fragile"
        • Column: Beyond Science
        • CiS 2012 Student Essay Contest: Runner Up
        • Essay: Why Awe?
        • CiS 2012 Student Essay Contest: First Place
        • Column: Great Gravity! "A Bit of Perspective"
        • Column: Modern Frontiers, Ancient Faith
        • Column: Time Capsule
      • Fall 12 >
        • Letter from the Editor: Fall 2012
        • The Director's Corner
        • Column: Faith on the Field
        • Comic: "Education"
        • Interview: Greetings from Mars!
        • Column: Clearing the Middle Path
        • Photo Essay: "Conversing with Nature"
        • Comic: "Abe"
        • Essay: Evolution and Imago Dei
        • Poem: "Locus Iste"
        • Levity: Beyond Science
        • Essay: God, Occam, and Science
        • Opinion: Humility and Grace
        • Levity: Great Gravity! "The College Years"
        • Poem: "Q.E.D."
        • Essay: My Overlapping Magisteria
        • Column: Time Capsule
      • Summer 12 >
        • Table of Contents
        • Letter from the Editor: Summer 2012
        • Director's Corner
        • Column: Faith on the Field
        • Column: Modern Frontiers, Ancient Faith
        • Comic: "Seminary"
        • Poem: "Temptation in the Wired Wilderness"
        • Levity: Beyond Science
        • Opinion: "The Breaking Bread"
        • Comic: "Humor"
        • Column: Clearing the Middle Path
        • Poem: "Ziggurat (and Helix)"
        • Levity: Great Gravity! "The Grade School Years"
        • Opinion: "Adam and the Origin of Man"
        • Poem: "Missa Solemnis"
        • Column: Time Capsule
      • Spring 12 >
        • Table of Contents
        • Letter from the Editor: Spring 2012
        • Director's corner
        • Column: Faith on the Field
        • Column: Time Capsule
        • Poem: "From Where do We Come?"
        • Featured Scientist
        • Levity: Beyond Science
        • Essay: "Faith and Science"
        • Fiction: "A Matter of Dust"
        • Levity: Great Gravity! "The Early Years"
        • Opinion: "Phony Environmental Theology"
        • Fiction: "Illumination"
        • Interview: "Process"
        • Column: Modern Frontiers, Ancient Faith
      • Spring 13 >
        • Letter from the Editor: Spring 2013
        • Column: Faith on the Field
        • Faith on the Field, cont.
        • Poem: Scientist's Psalm
        • Essay: A Downcast Spirit Dries Up the Bones: More perspectives on depression
        • Artwork: "Lipo Osteo" by Harold Sikkema
        • Feature: The Bible, Evolution, and Grace
        • Column: Beyond Science
        • Book Review: Prisoners of Hope
        • Column: Great Gravity! "The Grad School Years"
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Acts of God: Are all mutations random?

Picture
by Sy Garte

I have hitherto sometimes spoken as if the variations…were due to chance. This, of course is a wholly incorrect expression, but it serves to acknowledge plainly our ignorance of the cause of each particular variation.

—Charles Darwin, Origin of Species

We know that viruses can mutate to more lethal or more contagious forms. We have all been told to take the antibiotic for the full 10-day period, even if we start to feel better sooner. And we know that this is because the bacteria that caused the infection are not all killed right away, and that because of genetic variation among the bacteria, the most resistant ones will persist and flourish to cause new problems if we don’t zap them with the full dose. This is a good illustration of natural selection at work, the very same mechanism that drives evolution. And the key step, both for the kind of “micro evolution” whereby bacteria become resistant to a drug, and for the macro evolution whereby new species emerge from common ancestors, is mutation.

The connection between health and evolution is not trivial. From bacterial infections to cancer, the immune system to virology, the very same fundamental biological mechanisms of genetic variation and natural selection that Darwin first elucidated are in operation. Standard Darwinian evolutionary theory is based on a two-step process, wherein mutations are produced in a random manner, allowing for the basis of inherited variability. The second step, the selection of variants with an advantage in fitness, is decidedly nonrandom, and is overwhelmingly dependent on the precise environmental conditions prevailing upon individual organisms. Thus, bacteria that have undergone a mutation in one or more transport genes, will not be able to incorporate the toxic drug, and therefore become resistant to its lethal effect. These lucky bacteria will continue to thrive in your lungs and nose, and will rapidly take over from their dead and dying, unmutated cousins.

But, are we sure that this is really due to luck? In other words are all mutations, (whether they lead to drug resistance, or to new species) always and truly random chance events?

The idea that Darwinian evolution by the process of natural selection is based, at least partially, on a random process of mutation has been of particular concern to many Christians. The random nature of one aspect of the mechanism for evolution might appear to be at odds with the concept of an omniscient God, who is actively engaged in His creation throughout history. The idea that all mutations, the driver of variation among organisms, is driven only by chance, is clearly a stumbling block in the acceptance of evolution by some Christians.

This issue is connected with the larger question of teleology in evolution. Did God set up life with the innate capacity to evolve, and then hope for the best? Was man an inevitable result of evolution? Was God lucky that we emerged as creatures with the ability and desire to know and worship him? Or, is there a hidden purpose in the slow, meandering trail of increasing complexity that marks the evolutionary path from bacteria to slime molds, algae to conifers, worms to wombats, and apes to men?

Even before the discovery of DNA as the genetic molecule, biologists were examining mutations in experimental systems of bacteria, to answer the question about purpose and chance in mutation production. Do bacteria tend to specifically mutate those genes that would help them survive an environmental stress, such as starvation or toxic drugs, or do they simply generate random mutations, and then selection chooses which ones allow for increased fitness? This is a complex question to be addressed experimentally, but Luria and Delbruck in the 1940s seemed to have answered it with an elegant system called fluctuation analysis. The results of these experiments were clear: mutations were random, and then selected for their relative fitness. From this arose what has been called the Neo Darwinian synthesis, with molecular genetics playing the key role in the production of phenotypic variation, and with a confirmation of the idea that purpose is replaced by chance in the mechanism of the first stage of evolution.

This idea became engrained in the biological dogma, and as more and more data regarding the nature of genes and how they operate and change became available, the prevailing consensus grew stronger. Mutations are random, and there is no direction to how organisms change, other than the effects of post hoc selection based on relative fitness. Everything fit together well, and evolution became a theory that neither required, nor admitted to any degree of purpose or design.

But the absence of evidence is not evidence (let alone proof) of absence. Occam’s Razor is, after all, a useful philosophical tool, but it is not a law of nature. The strict application of Occam’s razor to biology would lead us to get most of cellular biochemistry wrong. So, although we know that teleology is not required for evolution, there is also nothing to suggest that teleology is impossible.

We should keep in mind that Darwin himself said nothing about whether the source of variation (mutations) was due to chance or not. As the quote above demonstrates, he simply had no idea, and more importantly, the distinction between chance and purpose really had no direct consequence on the general theory.

In 1988, the biological world was rocked by a paper in Nature by John Cairns and his colleagues that presented data showing that bacteria could indeed produce more frequent beneficial mutations than expected in order to relieve severe stress imposed by experimental conditions. These beneficial mutations (now called stress directed mutations or SDM) were produced at rates up to five times higher than other mutations with neutral effects.  While Cairns was not the first to report such findings, his paper seemed to take a major step away from the purely random concept for mutation. Since then, a large body of literature has confirmed and extended these conclusions. In addition, researchers have shed a great deal of light on the probable mechanisms by which bacteria seem to “choose” which genes to mutate for their own benefit. 

Several investigators have found evidence that SDM mutants in starving bacteria arise from different molecular mechanisms than ordinary mutational events.  Stress leads to derepression of specific genes, whose functions are related to the stress. The resulting higher level of transcription of these genes allows for unpaired and exposed bases in loop structures, as well as DNA supercoiling, that are more susceptible to mutation. Researchers have also found possible roles for transposons (genes that jump around the genome) and plasmids (small pieces of DNA, loose in bacteria) in some instances of SDM. Hypermutability of specific stress-related genes, can result from a variety of environmental stressors, like starvation, temperature, or anaerobiosis (life sustained by an organism in the absence of oxygen).

While a great deal of research into SDM remains to be done, (for example there is no data on SDM in “higher,” multicellular animals) the key point to be made here is less scientific than philosophical.

The answer to the question of whether there is any evidence of teleology in the production of specific mutations by any organism is now clearly yes, regardless of what the mechanism responsible is. The results to date are sufficient to put to rest the concept that all mutations are always produced by purely random processes. Purpose is still purpose, whether it springs from the hand of God, the mind of man, or the genome of E coli. Those “lucky” bacteria that survived the onslaught of an antibiotic might be less lucky, and more skillful at producing the perfect mutation, than we used to think.

So are there any implications from these scientific findings for a Christian perspective of Darwinian evolution? I would certainly think so. We cannot do the same experiments in animals as easily as we can in bacteria, but there are some approaches to look for evidence of past SDM during evolution in the genomes of various species, using the massive genetic data sets that are available. And if such evidence is found, we might see that non random mutations, purposeful changes in the DNA sequence, could be behind some of the more important evolutionary advances in the history of life.

If that is true, then it isn’t too much of a stretch to postulate a divine role in evolution. The driver of both the mutational and selection phases of evolution would then be environmental change. This includes severe global change brought about by an asteroid impact, or by volcanism or plates shifting, or perhaps even more minor, local changes, such as those brought about in typical “Acts of God” like storms, floods, droughts, and so on. Stress directed (non random) mutations could be one way that God steps in to guide the process of biological progression during evolution, to advance his will, his goals, and his purpose.


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God & Nature magazine is a publication of the American Scientific Affiliation, an international network of Christians in science: www.asa3.org